CSTF3 Antikörper (AA 151-250) (Cy5)
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- Target Alle CSTF3 Antikörper anzeigen
- CSTF3 (Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 3, 77kDa (CSTF3))
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Bindungsspezifität
- AA 151-250
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CSTF3 Antikörper ist konjugiert mit Cy5
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Maus
- Homologie
- Human,Rat,Dog,Cow,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CSTF3/CSTF77
- Isotyp
- IgG
- Top Product
- Discover our top product CSTF3 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CSTF3 (Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 3, 77kDa (CSTF3))
- Andere Bezeichnung
- CSTF3/CSTF77 (CSTF3 Produkte)
- Synonyme
- cstf3 antikoerper, MGC76035 antikoerper, CSTF3 antikoerper, wu:fa99c02 antikoerper, wu:fb18b09 antikoerper, zgc:56028 antikoerper, 4732468G05Rik antikoerper, C79532 antikoerper, CstF-77 antikoerper, cstf3a antikoerper, CSTF-77 antikoerper, cleavage stimulation factor, 3' pre-RNA, subunit 3 antikoerper, cleavage stimulation factor subunit 3 antikoerper, cstf3 antikoerper, CSTF3 antikoerper, LOC100544392 antikoerper, LOC100641283 antikoerper, Cstf3 antikoerper, cstf3.S antikoerper
- Hintergrund
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Synonyms: CF 1 77 kDa subunit, Cleavage stimulation factor 77 kDa subunit, Cleavage stimulation factor subunit 3, Cleavage stimulation factor subunit 3 isoform 1, CSTF 3, CSTF 77, CSTF 77 kDa subunit, CSTF77, MGC117398, MGC43001, MGC75122, CSTF3_HUMAN.
Background: Polyadenylation of mRNA precursors is a two-step reaction that requires multiple protein factors. The first step, endonucleolytic cleavage of polyadenylation substrates, requires CstF (cleavage stimulation factor), a heterotrimer that is composed of three distinct subunits. Heterotrimeric CstF recognizes GU- and U-rich sequences located downstream of the polyadenylation site on RNA. CstF-77 (cleavage stimulation factor, 77 kDa subunit), also known as CstF3, is one of the three subunits comprising CstF. It can exist as a homodimer and functions as the bridge, directly interacting with the other two CstF subunits, namely CstF-64 and CstF-50. CstF-77 is highly conserved among eukaryotes. It contains an Alpha-helical structure with 11 HAT (Half-a-TPR-containing) repeats and is essential for CstF assembly. In addition, CstF-77 is capable of interacting with CPSF1 and FCP1, other factors involved in polyadenylation.
- Gen-ID
- 1479
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