DRAXIN Antikörper (AA 251-349) (Cy5)
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- Target Alle DRAXIN Antikörper anzeigen
- DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))
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Bindungsspezifität
- AA 251-349
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DRAXIN Antikörper ist konjugiert mit Cy5
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Applikation
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Homologie
- Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human C1orf187
- Isotyp
- IgG
- Top Product
- Discover our top product DRAXIN Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))
- Andere Bezeichnung
- C1orf187 (DRAXIN Produkte)
- Synonyme
- C1orf187 antikoerper, draxin antikoerper, AGPA3119 antikoerper, UNQ3119 antikoerper, neucrin antikoerper, 2610109H07Rik antikoerper, MGC113312 antikoerper, dorsal inhibitory axon guidance protein antikoerper, DRAXIN antikoerper, Draxin antikoerper, draxin antikoerper
- Hintergrund
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Synonyms: AGPA3119, C1orf187, Chromosome 1 open reading frame 187, Dorsal inhibitory axon guidance protein, Dorsal repulsive axon guidance protein, DRAXI_HUMAN, Draxin, FLJ34999, MGC117222, Neucrin, OTTHUMP00000002262, UNQ3119.
Background: C1orf187, also known as Draxin, Dorsal repulsive axon guidance protein and Neucrin, is a 349 amino acid secreted protein that is required of the development of the spinal cord and forebrain commissures. C1orf187 acts as a chemorepulsive guidance protein and directs commissural axons during development by repelling neurite outgrowth from the spinal cord. During development, C1orf187 modulates neural crest migration by reducing the polarization of these cells, leading to reduced velocity of migration and increased frequency of changing direction, leading to a net decrease in migrational distance. It acts as an antagonist of the Wnt signaling pathway by inhibiting the stabilization of cytosolic _-catenin via its interaction with LRP6. C1orf187 inhibits outgrowth from the olfactory bulb and likely contributes to the formation of the lateral olfactory tract.
- Gen-ID
- 374946
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