GCM2 Antikörper (AA 61-160) (Cy5)

Produktnummer ABIN1704574

Produktdetails anti-GCM2 Antikörper (Cy5)

Target: GCM2 (Glial Cells Missing Homolog 2 (GCM2))

Bindungsspezifität: AA 61-160

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCM2 Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GCM2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GCM2

Target: GCM2 (Glial Cells Missing Homolog 2 (GCM2))

Andere Bezeichnung: GCM2 (GCM2 Produkte)

Synonyme: GCMb antikoerper, Gcm-2 antikoerper, gcm-2 antikoerper, GCMB antikoerper, hGCMb antikoerper, Gcm-rs1 antikoerper, Gcm1 antikoerper, Gcm1-rs2 antikoerper, glial cells missing homolog 2 antikoerper, glial cells missing homolog 2 (Drosophila) antikoerper, glial cells missing homolog 2 S homeolog antikoerper, GCM2 antikoerper, gcm2 antikoerper, gcm2.S antikoerper, Gcm2 antikoerper

Hintergrund:

Synonyms: Chorion-specic transcription factor GCMb, GCM mot protein 2, GCMb, Glial cells missing homolog 2, glial cells missing homolog b, GCM2_HUMAN.

Background: Glial cells missing homolog 2 (GCM2), also known as Chorion-specific transcription factor GCMb, is a 506 amino acid nuclear protein. GCM2 is a transcription factor that acts as an essential regulator of parathyroid development. GCM2 is also thought to mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. GCM2 contains one N-terminal GCM domain, which has DNA binding activity. Mutations of the gene that encodes GCM2 are associated with hypoparathyroidism, an autosomal recessive condition characterized by hypocalcemia and hyperphosphatemia.

Gen-ID: 9247

UniProt: O75603