CHTOP Antikörper (AA 31-130) (Cy7)

Produktnummer ABIN1708015

Produktdetails anti-CHTOP Antikörper (Cy7)

Target: CHTOP (Chromatin Target of PRMT1 (CHTOP))

Bindungsspezifität: AA 31-130

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHTOP Antikörper ist konjugiert mit Cy7

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf77

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CHTOP

Target: CHTOP (Chromatin Target of PRMT1 (CHTOP))

Andere Bezeichnung: C1orf77 (CHTOP Produkte)

Synonyme: C1orf77 antikoerper, FL-SRAG antikoerper, FOP antikoerper, RP1-178F15.2 antikoerper, SRAG antikoerper, SRAG-3 antikoerper, SRAG-5 antikoerper, pp7704 antikoerper, 2500003M10Rik antikoerper, C81330 antikoerper, Fop antikoerper, Srag antikoerper, C25H1orf77 antikoerper, C3H1orf77 antikoerper, c1orf77 antikoerper, chtop antikoerper, fop antikoerper, srag antikoerper, fb17a05 antikoerper, wu:fb17a05 antikoerper, wu:fi05e09 antikoerper, zgc:55292 antikoerper, zgc:153909 antikoerper, chromatin target of PRMT1 antikoerper, chromatin target of PRMT1 S homeolog antikoerper, chromatin target of PRMT1 protein antikoerper, chromatin target of PRMT1a antikoerper, chromatin target of PRMT1b antikoerper, CHTOP antikoerper, Chtop antikoerper, chtop.S antikoerper, LOC100344922 antikoerper, chtopa antikoerper, chtopb antikoerper

Hintergrund:

Synonyms: Chromatin target of PRMT1 protein, Chromosome 1 open reading frame 77, CHTOP, CHTOP_HUMAN, DKFZp547E1010, FOP, Friend of PRMT1 protein, MGC131924, MGC86949, OTTHUMP00000035122, OTTHUMP00000035123, Pp7704, RP1 178F15.2, Small arginine- and glycine-rich protein, Small protein rich in arginine and glycine, SRAG.

Background: C1orf77, also known as Friend of PRMT1 protein, is a 248 amino acid protein that plays an essential role in the ligand-dependent activation of estrogen receptor target genes. C1orf77 is tightly associated with chromatin and is modified by both asymmetric and symmetric arginine methylation. Depletion of C1orf77 results in almost complete block of estradiol-induced promter occupancy by the estrogen receptor. Also, complete knockdown of C1orf77 mRNA in adult erythroid progenitors stongly induces fetal hemoglobin, suggesting that C1orf77 is a critical modulator of _-globin gene expression. There are two isoforms of C1orf77 that are produced as a result of alternative splicing events. The gene encoding C1orf77 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.

Gen-ID: 26097