GLI4 Antikörper (AA 271-376) (Cy7)

Produktnummer ABIN1708912

Produktdetails anti-GLI4 Antikörper (Cy7)

Target: GLI4 (GLI Family Zinc Finger Protein 4 (GLI4))

Bindungsspezifität: AA 271-376

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLI4 Antikörper ist konjugiert mit Cy7

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GLI4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GLI4

Target: GLI4 (GLI Family Zinc Finger Protein 4 (GLI4))

Andere Bezeichnung: GLI4 (GLI4 Produkte)

Synonyme: HKR4 antikoerper, ZNF928 antikoerper, GLI4 antikoerper, GLI family zinc finger 4 antikoerper, RIKEN cDNA 9130023H24 gene antikoerper, GLI4 antikoerper, 9130023H24Rik antikoerper, Gli4 antikoerper

Hintergrund:

Synonyms: GLI 4, GLI Kruppel family member GLI 4, GLI Kruppel family member GLI4, GLI4, GLI4_HUMAN, HKR 4, HKR4, HKR4 protein, Krueppel related zinc finger protein 4, Krueppel-related zinc finger protein 4, Neural specic DNA binding protein, Oncogene HKR 4, Oncogene HKR4, Protein HKR 4, Protein HKR4, Zinc finger protein GLI 4, Zinc finger protein GLI4.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. GLI-4, also known as HKR4, is a 376 amino acid protein that localizes to the nucleus and contains seven C2H2-type zinc fingers. Belonging to the krueppel C2H2-type zinc-finger protein family, GLI-4 may function as a transcriptional regulator, effectively activating or repressing the transcription of target genes. The gene encoding GLI-4 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.

Gen-ID: 2738