MEGF10 Antikörper (AA 55-150) (FITC)

Produktnummer ABIN1709913

Produktdetails anti-MEGF10 Antikörper (FITC)

Target: MEGF10 (Multiple EGF-Like-Domains 10 (MEGF10))

Bindungsspezifität: AA 55-150

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MEGF10 Antikörper ist konjugiert mit FITC

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MEGF10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu MEGF10

Target: MEGF10 (Multiple EGF-Like-Domains 10 (MEGF10))

Andere Bezeichnung: MEGF10 (MEGF10 Produkte)

Synonyme: EMARDD antikoerper, 3000002B06Rik antikoerper, Gm331 antikoerper, multiple EGF-like domains 10 antikoerper, multiple EGF like domains 10 antikoerper, multiple EGF-like-domains 10 antikoerper, Megf10 antikoerper, MEGF10 antikoerper

Hintergrund:

Synonyms: MEG10_HUMAN, MEGF protein, megf10, Multiple EGF-like domains protein 10, multiple EGF-like-domains 10, Multiple epidermal growth factor-like domains 10, Multiple epidermal growth factor-like domains protein 10.

Background: MEGF10 is a 1,140 amino acid protein encoded by the human gene MEGF10. MEGF10 belongs to the MEGF family and contains fifteen EGF-like domains and one EMI domain. The engulfment of dying cells is a specialized form of phagocytosis that is highly conserved across evolution and is mediated by the concerted action of several molecules. MEGF10 is an engulfment receptor protein that localizes to the plasma membrane in a punctuated pattern. The MEGF10 protein shares structural similarities with nematode engulfment receptor cell death abnormal-1 (CED-1). MEGF10 function is modulated by the ATP binding cassette transporter ABCA1, which is an ortholog to CED-7. It is expressed at the cell surface in clusters around cell corpses during engulfment, and during the engulfment of apoptotic thymocytes is recruited to the bottom of the forming phagocytic cup.

Gen-ID: 84466

Pathways: Regulation of Muscle Cell Differentiation