GFM2 Antikörper (AA 151-250) (FITC)

Produktnummer ABIN1710501

Produktdetails anti-GFM2 Antikörper (FITC)

Target: GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))

Bindungsspezifität: AA 151-250

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFM2 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GFM2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GFM2

Target: GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))

Andere Bezeichnung: GFM2 (GFM2 Produkte)

Hintergrund:

Synonyms: EF-G2mt, EFG2, EFG2mt, elongation factor G 2, mitochondrial, Elongation factor G2, G elongation factor mitochondrial 2, GFM2, hEFG2, mEFG 2, mEFG2, Mitochondrial elongation factor G2, mitochondrial ribosome recycling factor 2, MRRF2, MST027, MSTP027, OTTHUMP00000222951, OTTHUMP00000222952, ribosome-releasing factor 2, mitochondrial, RRF2, RRF2mt.

Background: GFM2 is a mitochondrial translation elongation factor. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA.

Gen-ID: 84340

UniProt: Q969S9

Pathways: Ribonucleoprotein Complex Subunit Organization