GOT1L1 Antikörper (AA 201-300) (FITC)
-
- Target Alle GOT1L1 Produkte
- GOT1L1 (Glutamic-Oxaloacetic Transaminase 1-Like 1 (GOT1L1))
-
Bindungsspezifität
- AA 201-300
-
Reaktivität
- Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser GOT1L1 Antikörper ist konjugiert mit FITC
-
Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Maus, Ratte
- Homologie
- Human,Cow,Sheep,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GOT1L1
- Isotyp
- IgG
-
-
- Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- GOT1L1 (Glutamic-Oxaloacetic Transaminase 1-Like 1 (GOT1L1))
- Andere Bezeichnung
- GOT1L1 (GOT1L1 Produkte)
- Synonyme
- 1700083M11Rik antikoerper, RGD1307172 antikoerper, glutamic-oxaloacetic transaminase 1 like 1 antikoerper, glutamic-oxaloacetic transaminase 1-like 1 antikoerper, GOT1L1 antikoerper, Got1l1 antikoerper
- Hintergrund
-
Synonyms: AATC2_HUMAN, cytoplasmic 2, Glutamate oxaloacetate transaminase 1-like protein 1, Glutamic oxaloacetic transaminase 1 like 1, GOT1L1, Putative aspartate aminotransferase, Putative aspartate aminotransferase, cytoplasmic 2, Transaminase A-like protein 1.
Background: GOT1L1, Glutamate oxaloacetate transaminase 1-like protein 1, is a 421 amino acid member of the class-I pyridoxal-phosphate-dependent aminotransferase family. Similar to glutamate-oxaloacetate transaminase (GOT1), GOT1L1 is found primarily as a homodimer in the cytoplasmic space but also has mitochondrial and chloroplastic isozymes. GOT1L1 transaminates 2-oxoglutarate with L-aspartate to yield oxaloacetate and L-glutamate. This reaction requires a pyridoxal phosphate cofactor to occur. The GOT1L1 peptidase is predominately expressed in the liver and serum levels of this protein can be used as an indicator of liver disease. Also, elevated glutamate concentrations in the brain interstitial fluids can lead to pathological brain conditions. The glutamate-scavenging properties of these aminotranferase type enzymes likely prevent glutamate excitotoxicity and the long-lasting neurological deficits seen after stroke.
- Gen-ID
- 137362
-