GBGT1 Antikörper (AA 251-347) (HRP)

Produktnummer ABIN1711827

Dieses Anti-GBGT1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GBGT1 in WB, ELISA, IHC (fro) und IHC (p). Geeignet für Human.

Kurzübersicht für GBGT1 Antikörper (AA 251-347) (HRP) (ABIN1711827)

Target: GBGT1 (Globoside alpha-1,3-N-Acetylgalactosaminyltransferase 1 (GBGT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GBGT1 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GBGT1 Antikörper (HRP)

Bindungsspezifität: AA 251-347

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GBGT1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GBGT1

Target: GBGT1 (Globoside alpha-1,3-N-Acetylgalactosaminyltransferase 1 (GBGT1))

Andere Bezeichnung: GBGT1

Hintergrund:

Synonyms: 3-N-acetylgalactosaminyltransferase 1, A3GALNT, EC=2.4.1.-, Forssman glycolipid synthase-like protein, Forssman glycolipid synthetase FS, Forssman synthetase, FS, GBGT1, GBGT1_HUMAN, Globoside alpha-1, globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, glycolipid synthase-like protein, RP11-326L24.6, UNQ2513, UNQ2513/PRO6002.

Background: GBGT1 is a 347 amino acid single-pass type II membrane protein that belongs to the glycosyltransferase 6 family. Localizing to the golgi apparatus membrane, GBGT1 is widely expressed, with high levels found in placenta, ovary and peripheral blood leukocyte, and lower levels expressed in liver, thymus and testis. GBGT1 utilizes manganese as a cofactor, and assists in the addition of N-acetylgalactosamine (GalNAc) in alpha-1,3-linkage to various substrates, resulting in the formation of glycolipids. Glycolipids are present in most eukaryotic cells and may assist in the adherence of certain pathogens. Existing as two alternatively spliced isoforms, the gene encoding GBGT1 maps to human chromosome 9q34.2 and mouse chromosome 2 A3.

Gen-ID: 26301