GATA2 Antikörper (pSer401) (HRP)
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- Target Alle GATA2 Antikörper anzeigen
- GATA2 (GATA Binding Protein 2 (GATA2))
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Bindungsspezifität
- pSer401
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GATA2 Antikörper ist konjugiert mit HRP
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human
- Homologie
- Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human GATA2 around the phosphorylation site of Ser401
- Isotyp
- IgG
- Top Product
- Discover our top product GATA2 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handhabung
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- GATA2 (GATA Binding Protein 2 (GATA2))
- Andere Bezeichnung
- GATA2 (GATA2 Produkte)
- Synonyme
- DCML antikoerper, MONOMAC antikoerper, NFE1B antikoerper, Gata-2 antikoerper, xgata-2 antikoerper, xgata2 antikoerper, GATA-2 antikoerper, NF-E1b antikoerper, GATA2 antikoerper, Gata2 antikoerper, gata2 antikoerper, zg2 antikoerper, zgc:91840 antikoerper, GATA binding protein 2 antikoerper, GATA binding protein 2 L homeolog antikoerper, amidase antikoerper, glutamyl/aspartyl-tRNA(Gln/Asp) amidotransferasesubunit A antikoerper, hypothetical protein antikoerper, glutamyl-tRNA(Gln) amidotransferase, subunit GatA (Glu-ADT subunit A) antikoerper, GATA2 transcription factor antikoerper, putative gata binding factor antikoerper, GATA binding protein 2a antikoerper, GATA binding protein 2b antikoerper, GATA2 antikoerper, Gata2 antikoerper, gata2.L antikoerper, RR_RS20245 antikoerper, gatA2 antikoerper, Smp_018590 antikoerper, gata2a antikoerper, gata2b antikoerper
- Hintergrund
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Synonyms: GATA2 phospho S401, p-GATA2 phospho S401, GATA-2, GATA 2, GATA Binding Protein 2, GATA-binding protein 2, Gata2, GATA2_HUMAN, MGC2306, NFE 1B, NFE1B.
Background: Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as in erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. Both GATA-4 and GATA-6 are found in heart, pancreas and ovary, lung and liver tissues exhibit GATA-6, but not GATA-4 expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites.
- Gen-ID
- 2624
- Pathways
- Stem Cell Maintenance
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