GLUD2 Antikörper (PE-Cy5)

Produktnummer ABIN1713017

Produktdetails anti-GLUD2 Antikörper (PE-Cy5)

Target: GLUD2 (Glutamate Dehydrogenase 2 (GLUD2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLUD2 Antikörper ist konjugiert mit PE-Cy5

Applikation: Western Blotting (WB)

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GLUD2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GLUD2

Target: GLUD2 (Glutamate Dehydrogenase 2 (GLUD2))

Andere Bezeichnung: GLUD2 (GLUD2 Produkte)

Synonyme: GDH2 antikoerper, GLUDP1 antikoerper, GLUTAMATE DEHYDROGENASE 2 antikoerper, T2I1.150 antikoerper, T2I1_150 antikoerper, glutamate dehydrogenase 2 antikoerper, glutamate dehydrogenase 2 antikoerper, glutamate dehydrogenase antikoerper, GLUD2 antikoerper, GDH2 antikoerper, NP_RS03950 antikoerper

Hintergrund:

Synonyms: GDH 2, GDH, GDH2, GLUDP1, Glutamate dehydrogenase 2, Glutamate dehydrogenase 2 mitochondrial, Glutamate dehydrogenase pseudogene 1.

Background: GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family. Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission. GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP. Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. GLUD2 is expressed in testis and retina, with lower levels found in brain.

Gen-ID: 2747

Pathways: Synaptic Membrane