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GLUD2 Antikörper (PE-Cy7)

GLUD2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund WB Wirt: Kaninchen Polyclonal PE-Cy7
Produktnummer ABIN1713285
  • Target Alle GLUD2 Antikörper anzeigen
    GLUD2 (Glutamate Dehydrogenase 2 (GLUD2))
    Reaktivität
    • 53
    • 7
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund
    Wirt
    • 49
    • 4
    Kaninchen
    Klonalität
    • 52
    • 1
    Polyklonal
    Konjugat
    • 20
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GLUD2 Antikörper ist konjugiert mit PE-Cy7
    Applikation
    • 47
    • 20
    • 13
    • 13
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GLUD2
    Isotyp
    IgG
    Top Product
    Discover our top product GLUD2 Primärantikörper
  • Applikationshinweise
    FCM(1:100-500)
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    GLUD2 (Glutamate Dehydrogenase 2 (GLUD2))
    Andere Bezeichnung
    GLUD2 (GLUD2 Produkte)
    Synonyme
    GDH2 antikoerper, GLUDP1 antikoerper, GLUTAMATE DEHYDROGENASE 2 antikoerper, T2I1.150 antikoerper, T2I1_150 antikoerper, glutamate dehydrogenase 2 antikoerper, glutamate dehydrogenase 2 antikoerper, glutamate dehydrogenase antikoerper, GLUD2 antikoerper, GDH2 antikoerper, NP_RS03950 antikoerper
    Hintergrund

    Synonyms: GDH 2, GDH, GDH2, GLUDP1, Glutamate dehydrogenase 2, Glutamate dehydrogenase 2 mitochondrial, Glutamate dehydrogenase pseudogene 1.

    Background: GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family. Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission. GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP. Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. GLUD2 is expressed in testis and retina, with lower levels found in brain.

    Gen-ID
    2747
    Pathways
    Synaptic Membrane
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