GLUD2 Antikörper (PE-Cy7)
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- Target Alle GLUD2 Antikörper anzeigen
- GLUD2 (Glutamate Dehydrogenase 2 (GLUD2))
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GLUD2 Antikörper ist konjugiert mit PE-Cy7
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Applikation
- Western Blotting (WB)
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GLUD2
- Isotyp
- IgG
- Top Product
- Discover our top product GLUD2 Primärantikörper
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- Applikationshinweise
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FCM(1:100-500)
Optimal working dilution should be determined by the investigator. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- GLUD2 (Glutamate Dehydrogenase 2 (GLUD2))
- Andere Bezeichnung
- GLUD2 (GLUD2 Produkte)
- Synonyme
- GDH2 antikoerper, GLUDP1 antikoerper, GLUTAMATE DEHYDROGENASE 2 antikoerper, T2I1.150 antikoerper, T2I1_150 antikoerper, glutamate dehydrogenase 2 antikoerper, glutamate dehydrogenase 2 antikoerper, glutamate dehydrogenase antikoerper, GLUD2 antikoerper, GDH2 antikoerper, NP_RS03950 antikoerper
- Hintergrund
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Synonyms: GDH 2, GDH, GDH2, GLUDP1, Glutamate dehydrogenase 2, Glutamate dehydrogenase 2 mitochondrial, Glutamate dehydrogenase pseudogene 1.
Background: GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family. Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission. GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP. Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. GLUD2 is expressed in testis and retina, with lower levels found in brain.
- Gen-ID
- 2747
- Pathways
- Synaptic Membrane
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