HGD Antikörper (AA 351-445)

Produktnummer ABIN1713533

Produktdetails anti-HGD Antikörper

Target: HGD (Homogentisate 1,2-Dioxygenase (HGD))

Bindungsspezifität: AA 351-445

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HGD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HGD

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu HGD

Target: HGD (Homogentisate 1,2-Dioxygenase (HGD))

Andere Bezeichnung: HGD (HGD Produkte)

Synonyme: CG4779 antikoerper, Dmel\\CG4779 antikoerper, PSPTO3551 antikoerper, DDBDRAFT_0185702 antikoerper, DDBDRAFT_0191461 antikoerper, DDB_0185702 antikoerper, DDB_0191461 antikoerper, Hgo antikoerper, aku antikoerper, hgo antikoerper, AKU antikoerper, HGO antikoerper, homogentisate 1,2-dioxygenase antikoerper, Homogentisate 1,2-dioxygenase antikoerper, homogentisate 1, 2-dioxygenase antikoerper, homogentisate 1,2-dioxygenase L homeolog antikoerper, hgo antikoerper, HGD antikoerper, hmgA antikoerper, Shewana3_2481 antikoerper, hgd antikoerper, BC1002_0545 antikoerper, BC1003_0502 antikoerper, BC1001_0489 antikoerper, Sinme_2995 antikoerper, Sphch_0441 antikoerper, Hgd antikoerper, hgd.L antikoerper

Hintergrund:

Synonyms: 2-dioxygenase, AKU, FLJ94126, hgd, HGD_HUMAN, HGO, Homogentisate 1 2 dioxygenase, Homogentisate 1, Homogentisate oxidase, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.

Background: HGD is a 445 amino acid protein that belongs to the homogentisate dioxygenase family and is involved in the pathway of amino acid degradation. Expressed at high levels in kidney, colon, liver, prostate and small intestine, HGD uses iron as a cofactor to catalyze the oxygen-dependent conversion of homogentisate to 4-maleylacetoacetate, a reaction that is the fourth step in the creation of L-phenylalanine from fumarate and acetoacetic acid. Defects in the gene encoding HGD are the cause of alkaptonuria (AKU), an autosomal recessive disorder that is characterized by urine that turns dark on standing and alkalinization, black ochronotic pigmentation of cartilage and collagenous tissues and spine arthritis.

Gen-ID: 3081