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IgD Antikörper (AA 51-150)

Reaktivität: Human WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1713550
  • Target Alle IgD Antikörper anzeigen
    IgD
    Bindungsspezifität
    • 14
    • 6
    • 3
    • 3
    • 1
    • 1
    AA 51-150
    Reaktivität
    • 41
    • 10
    Human
    Wirt
    • 23
    • 18
    • 9
    Kaninchen
    Klonalität
    • 28
    • 22
    Polyklonal
    Konjugat
    • 13
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IgD Antikörper ist unkonjugiert
    Applikation
    • 22
    • 21
    • 12
    • 12
    • 10
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human IGHD
    Isotyp
    IgG
    Top Product
    Discover our top product IgD Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    IgD
    Andere Bezeichnung
    IGHD (IgD Produkte)
    Synonyme
    IgD antikoerper, Igh-5 antikoerper, immunoglobulin heavy constant delta antikoerper, immunoglobulin delta heavy chain constant region antikoerper, Ighd antikoerper, Igd antikoerper, IGHD antikoerper
    Substanzklasse
    Antibody
    Hintergrund

    Synonyms: IGHD, Constant region of heavy chain of IgD, Ig delta chain C region, Ig delta chain C region secreted form, IgD, Igh-5, Immunoglobulin delta, Immunoglobulin heavy constant delta, IGHD_HUMAN, Immunoglobulin heavy delta chain.

    Background: Ig delta chain C region is an allelic product of the human IGHD gene. The two known IGHD alleles, IGHD*01 and IGHD*02, respectively produce isoforms 1, a secreted protein, and 2, a single-pass type I membrane protein. A member of the adaptive immune system, IgD are monomers expressed by activated B cells. Containing 3 Ig-like (immunoglobulin-like) domains, IgD chain C is located on chromosome 14 within the human heavy chain locus, lying on the 3? side of the IgM chain C region from the V-D-J cassette. Polyadenylation at certain sites along the heavy chain locus likely effects the mechanism that determines the alternative splicing event which results in the expression of either IgD chain C or IgM chain C. Some studies have suggested that antigenic coactivation of IgD+ B cells can have a negative influence on bone resorption during infectious events.

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