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CTNS Antikörper (AA 231-330)

CTNS Reaktivität: Human ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1713755
  • Target Alle CTNS Antikörper anzeigen
    CTNS (Cystinosis, Nephropathic (CTNS))
    Bindungsspezifität
    • 8
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    AA 231-330
    Reaktivität
    • 25
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 22
    • 3
    Kaninchen
    Klonalität
    • 23
    • 2
    Polyklonal
    Konjugat
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser CTNS Antikörper ist unkonjugiert
    Applikation
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CTNS/Cystinosin
    Isotyp
    IgG
    Top Product
    Discover our top product CTNS Primärantikörper
  • Applikationshinweise
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CTNS (Cystinosis, Nephropathic (CTNS))
    Andere Bezeichnung
    CTNS (CTNS Produkte)
    Synonyme
    CTNS-LSB antikoerper, PQLC4 antikoerper, AI195360 antikoerper, AW049661 antikoerper, zgc:110194 antikoerper, CTNS antikoerper, cystinosin, lysosomal cystine transporter antikoerper, cystinosis, nephropathic antikoerper, cystinosin, lysosomal cystine transporter L homeolog antikoerper, CTNS antikoerper, Ctns antikoerper, ctns antikoerper, ctns.L antikoerper
    Hintergrund

    Synonyms: CTNS LSB, Cystinosin, cystinosis, nephropathic, PQLC4, CTNS_HUMAN.

    Background: Cystinosis is an autosomal recessive disorder resulting from defective lysosomal transport of cystine and present at birth as a failure to thrive, rickets and proximal renal tubular acidosis. The human CTNS gene on chromosome 17p13 encodes the protein Cystinosin, and mutations in CTNS are responsible for nephropathic cystinosis. The CTNS promoter contains an Sp1 binding element. Cystinosin is an integral membrane protein containing 7 transmembrane domains that functions as a H+-driven transporter responsible for cystine export from lysosomes. In humans, Cystinosin is expressed abundantly in pancreas, kidney (mature and fetal), and skeletal muscle. The mouse homolog to CTNS encodes a protein which is expressed in all tissues except skeletal muscle. In the cell, Cystinosin co-localizes with LAMP-2 to lysosomes. A C-terminal GYDQL sorting motif within Cystinosin is critical for lysosomal localization.

    Gen-ID
    1497
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