DLG5 Antikörper (AA 1801-1919)

Produktnummer ABIN1713763

Produktdetails anti-DLG5 Antikörper

Target: DLG5 (Discs, Large Homolog 5 (DLG5))

Bindungsspezifität: AA 1801-1919

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLG5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DLG5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu DLG5

Target: DLG5 (Discs, Large Homolog 5 (DLG5))

Andere Bezeichnung: DLG5 (DLG5 Produkte)

Synonyme: DLG5 antikoerper, dlg5 antikoerper, wu:fc28f03 antikoerper, LP-DLG antikoerper, P-DLG5 antikoerper, PDLG antikoerper, 4933429D20Rik antikoerper, T25557 antikoerper, mKIAA0583 antikoerper, discs large MAGUK scaffold protein 5 antikoerper, discs, large homolog 5 (Drosophila) antikoerper, discs, large homolog 5a (Drosophila) antikoerper, DLG5 antikoerper, dlg5a antikoerper, Dlg5 antikoerper

Hintergrund:

Synonyms: Discs large homolog 5 Drosophila, Discs large homolog 5, Discs large protein LP DLG, Discs large protein P dlg, Discs large protein P-dlg, Disks large homolog 5, DLG 5, DLG5, DLG5_HUMAN, KIAA0583, Large type of P DLG, LP DLG, P DLG5, PDLG, Placenta and prostate DLG.

Background: Membrane-associated guanylate kinase (MAGUK) family members function as molecular scaffolds for the assembly of multiprotein complexes localizing to the plasma membrane. Several mammalian proteins related to the Drosophila tumor suppressor discs-large (dlg) gene product belong to the MAGUK family. MAGUK family members include the postsynaptic proteins PSD-93, DLG5, Pals1, PSD-95 (SAP 90), densin-180, NE-dlg (SAP 120), dlg-1 (SAP 97), GKAP (GK-associated protein), p55, the tight junction associated proteins ZO-1-3 and the caspase-associated recruitment domain (CARD) proteins CARD6, CARD8-12 and CARD14. DLG5, a cell-cell junction peripheral membrane protein, plays an important role in maintaining the structure of epithelial cell plasma membranes. It also plays an important part in transmitting extracellular signals to the cytoskeleton and the membrane. DLG5 which can interact with MPP1 and CTNNB1, is primarily expressed in prostate and placenta.