FN3K Antikörper (AA 201-309)

Produktnummer ABIN1713787

Produktdetails anti-FN3K Antikörper

Target: FN3K (Fructosamine 3 Kinase (FN3K))

Bindungsspezifität: AA 201-309

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FN3K Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FN3K

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu FN3K

Target: FN3K (Fructosamine 3 Kinase (FN3K))

Andere Bezeichnung: FN3K (FN3K Produkte)

Synonyme: Afu1g07040 antikoerper, An07g09600 antikoerper, AO090012000956 antikoerper, 2310074G21Rik antikoerper, Fnsk antikoerper, fructosamine-3-kinase antikoerper, Fructosamine-3-kinase antikoerper, fructosamine 3 kinase antikoerper, AFUA_1G07040 antikoerper, ANI_1_1220064 antikoerper, GL50803_2969 antikoerper, AOR_1_1682194 antikoerper, BDBG_05694 antikoerper, VDBG_05566 antikoerper, BBMN68_411 antikoerper, Tsp_00557 antikoerper, Fn3k antikoerper, FN3K antikoerper

Hintergrund:

Synonyms: 2310074G21Rik, Fnsk, Fructosamine 3 kinase, RP23-293H17.4, FN3K_HUMAN.

Background: Amines, including those present on proteins, spontaneously react with glucose to make fructosamines in a reaction termed glycation. Fructosamine 3-kinase (FN3K), a 309-amino acid enzyme initially identified in erythrocytes, catalyzes the ATP-dependent phosphorylation of the third carbon on both D- and L-fructosamines, leading to their destabilization and eventually, their removal from the protein. FN3K is a monomer that is ubiquitously expressed in mammalian tissue and phosphorylates both low molecular mass and protein-bound fructosamines which are formed as a result of glycation of glucose with primary amines. FN3K protects proteins from the harmful effects of nonenzymatic glycation, and may also be involved in peptide repair and cell metabolism. FN3KRP (fructosamine-3-kinase-related protein) is a 309 amino acid protein that is expressed in erythrocytes, bone marrow, spleen, brain and kidney and belongs to the fructosamine kinase family. FN3KRP functions to phosphorylate psicoamines and ribulosamines on the third carbon of their sugar moiety, thereby leading to the deglycation of the target amines.

Gen-ID: 64122