FZD6 Antikörper (AA 11-110)

Produktnummer ABIN1713791

Produktdetails anti-FZD6 Antikörper

Target: FZD6 (Frizzled Family Receptor 6 (FZD6))

Bindungsspezifität: AA 11-110

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FZD6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus, Ratte

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Frizzled 6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu FZD6

Target: FZD6 (Frizzled Family Receptor 6 (FZD6))

Andere Bezeichnung: Frizzled 6 (FZD6 Produkte)

Synonyme: zgc:65879 antikoerper, zgc:77440 antikoerper, fz6 antikoerper, frz6 antikoerper, Xfrz6 antikoerper, frizzled6 antikoerper, frizzled-6 antikoerper, FZ-6 antikoerper, FZ6 antikoerper, HFZ6 antikoerper, NDNC10 antikoerper, Frizzled-6 antikoerper, Fz6 antikoerper, frizzled class receptor 6 antikoerper, frizzled class receptor 6 S homeolog antikoerper, fzd6 antikoerper, fzd6.S antikoerper, FZD6 antikoerper, Fzd6 antikoerper

Hintergrund:

Synonyms: FZ6, FZ-6, HFZ6, NDNC10, Frizzled-6, FZD6

Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

Gen-ID: 8323

UniProt: O60353

Pathways: WNT Signalweg, Tube Formation