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GADL1 Antikörper (AA 51-150)

GADL1 Reaktivität: Human IF (cc), IF (p), ELISA, IHC (fro), IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1713801
  • Target Alle GADL1 Produkte
    GADL1 (Glutamate Decarboxylase-Like 1 (GADL1))
    Bindungsspezifität
    • 14
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 51-150
    Reaktivität
    • 30
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 30
    Kaninchen
    Klonalität
    • 30
    Polyklonal
    Konjugat
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GADL1 Antikörper ist unkonjugiert
    Applikation
    • 12
    • 12
    • 9
    • 5
    • 2
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Homologie
    Human,Mouse,Rat,Bee
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GADL1
    Isotyp
    IgG
  • Applikationshinweise
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    GADL1 (Glutamate Decarboxylase-Like 1 (GADL1))
    Andere Bezeichnung
    GADL1 (GADL1 Produkte)
    Synonyme
    CSAD antikoerper, 1110027M19Rik antikoerper, RGD1565145 antikoerper, glutamate decarboxylase like 1 antikoerper, glutamate decarboxylase-like 1 antikoerper, GADL1 antikoerper, gadl1 antikoerper, Gadl1 antikoerper
    Hintergrund

    Synonyms: GADL1, GADL1_HUMAN, Glutamate decarboxylase like 1, Glutamate decarboxylase-like protein 1, MGC138191, OTTHUMP00000161199, OTTHUMP00000222306.

    Background: There are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 transiently activates to assist in GABA production. As a member of the group II decarboxylase family, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity. There are two isoforms of GADL1 that exist as a result of alternative splicing events.

    Gen-ID
    339896
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