GPR45 Antikörper (AA 251-350)

Produktnummer ABIN1713827

Produktdetails anti-GPR45 Antikörper

Target: GPR45 (G Protein-Coupled Receptor 45 (GPR45))

Bindungsspezifität: AA 251-350

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR45 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPR45

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu GPR45

Target: GPR45 (G Protein-Coupled Receptor 45 (GPR45))

Andere Bezeichnung: GPR45 (GPR45 Produkte)

Synonyme: GPR45 antikoerper, MGC97852 antikoerper, PSP24 antikoerper, PSP24(ALPHA) antikoerper, PSP24A antikoerper, 9230112G11Rik antikoerper, AW046772 antikoerper, LPA antikoerper, lpar-a antikoerper, xpsp24 antikoerper, G protein-coupled receptor 45 antikoerper, G protein-coupled receptor 45 L homeolog antikoerper, GPR45 antikoerper, gpr45 antikoerper, Gpr45 antikoerper, gpr45.L antikoerper

Hintergrund:

Synonyms: G protein coupled receptor 45, High affinity lysophosphatidic acid receptor, Probable G protein coupled receptor 45, GPCR 45, PSP24 1, PSP24 alpha, PSP24, PSP24ALPHA, PSP241, PSP24A.

Background: G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 54 (GPR54), a member of the rhodopsin family of GCPRs, is the receptor for the Kiss1 gene product, metastin. Mutations in GPCR54 are associated with a lack of puberty onset and autosomal recessive idiopathic hypogonadotropic hypogonadism, a deficient or decreased function of the gonads. Proper function of GRP54 is essential for puberty. In the rat, GRP54 is expressed in the liver, intestine and most areas of the brain, while in the human it is expressed in the placenta, pituitary, pancreas and spinal cord.

Gen-ID: 11250