NOB1 Antikörper

Produktnummer ABIN1713871

Produktdetails anti-NOB1 Antikörper

Target: NOB1 (RNA-Binding Protein NOB1 (NOB1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NOB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NOB1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NOB1

Target: NOB1 (RNA-Binding Protein NOB1 (NOB1))

Andere Bezeichnung: NOB1 (NOB1 Produkte)

Synonyme: MEE6.26 antikoerper, MEE6_26 antikoerper, Nob1p antikoerper, fc27e05 antikoerper, si:ch73-167i17.3 antikoerper, wu:fc27e05 antikoerper, ART-4 antikoerper, MST158 antikoerper, NOB1P antikoerper, PSMD8BP1 antikoerper, 1700021I09Rik antikoerper, Psmd8bp1 antikoerper, NIN1/PSMD8 binding protein 1 homolog antikoerper, RNA-binding NOB1-like protein antikoerper, RNA-binding protein nob1 antikoerper, RNA-binding protein NOB1 antikoerper, NIN1/RPN12 binding protein 1 homolog S homeolog antikoerper, NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) antikoerper, NIN1/RPN12 binding protein 1 homolog antikoerper, NOB1 antikoerper, AT5G41190 antikoerper, EDI_130960 antikoerper, CpipJ_CPIJ012739 antikoerper, BDBG_01281 antikoerper, PAAG_04204 antikoerper, PITG_13300 antikoerper, nob1.S antikoerper, nob1 antikoerper, Nob1 antikoerper

Hintergrund:

Synonyms: Adenocarcinoma antigen recognized by T lymphocytes 4, ART4, MST158, MSTP158, Nin one binding protein, NIN1/RPN12 binding protein 1 homolog S. cerevisiae, nob1, NOB1_HUMAN, NOB1P, Phosphorylation regulatory protein HP-10, Protein ART-4, Protein ART4, PSMD8 binding protein 1, PSMD8BP1, RNA binding protein NOB1, RNA-binding protein NOB1.

Background: NOB1P is a 412 amino acid nuclear protein that is involved in proteosome biogenesis and is required for the final step in 18S rRNA maturation. NOB1P contains a PIN domain, which functions as a nuclease in nonsense-mediated mRNA decay and is required for pre-rRNA cleavage. NOB1P interacts with Rent2, which is involved in nonsense-mediated decay of mRNAs containing premature stop codons. Expressed in placenta, spleen, endothelial cells, liver and lung, NOB1P is essential for the synthesis of 40S ribosome subunits. Supression of the gene encoding NOB1P inhibits the processing of the 20S pre-rRNA to the mature 18S rRNA, therefore leading to accumulation of high levels of 20S pre-rRNA with degradation intermediates.

Gen-ID: 28987

Pathways: Protein targeting to Nucleus