FAF2 Antikörper (AA 81-180)

Produktnummer ABIN1713972

Produktdetails anti-FAF2 Antikörper

Target: FAF2 (Fas Associated Factor Family Member 2 (FAF2))

Bindungsspezifität: AA 81-180

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Sheep,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ETEA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu FAF2

Target: FAF2 (Fas Associated Factor Family Member 2 (FAF2))

Andere Bezeichnung: ETEA (FAF2 Produkte)

Hintergrund:

Synonyms: AI462440, expressed in T cells and eosinophils in atopic dermatitis, faf2, FAF2_HUMAN, Fas associated factor family member 2, FAS-associated factor 2, KIAA0887, Protein ETEA, Protein expressed in T cells and eosinophils in atopic dermatitis, Protein expressed in T-cells and eosinophils in atopic dermatitis, UBX domain containing 8, UBX domain protein 3B, UBX domain-containing protein 3B, UBX domain-containing protein 8, UBXD8, UBXN3B.

Background: ETEA is a 445-amino acid protein associated with atopic dermatitis (AD), a chronic noncontagious relapsing inflammatory skin disease characterized by eczematous skin lesions and also referred to as eczematous dermatitis. Other atopic diseases such as hay fever, asthma and conjunctivitis often occur along with AD. ETEA shows higher expression in T cells and eosinophils of patients with AD than in T cells and eosinophils of unaffected individuals. T cells are influential in the regulation of the inflammatory process of this disease. The persistence of jAD is attributed to dysregulated apoptosis in T cells, eosinophils, and keratinocytes. ETEA may be involved in the resistance to apoptosis in T cells and eosinophils of AD patients.

Gen-ID: 23197