POLL Antikörper (AA 475-575)
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- Target Alle POLL Antikörper anzeigen
- POLL (Polymerase (DNA Directed), lambda (POLL))
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Bindungsspezifität
- AA 475-575
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Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser POLL Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- Kreuzreaktivität
- Ratte
- Homologie
- Human,Mouse,Dog,Cow,Sheep,Pig,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human DNA Polymerase lambda
- Isotyp
- IgG
- Top Product
- Discover our top product POLL Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- POLL (Polymerase (DNA Directed), lambda (POLL))
- Andere Bezeichnung
- DNA Polymerase lambda (POLL Produkte)
- Synonyme
- T10O24.13 antikoerper, T10O24_13 antikoerper, zgc:66320 antikoerper, zgc:77901 antikoerper, wu:fe49a04 antikoerper, beta-n antikoerper, pol-kappa antikoerper, BETAN antikoerper, POLKAPPA antikoerper, 1110003P06Rik antikoerper, AV007317 antikoerper, DNA polymerase lambda (POLL) antikoerper, DNA polymerase lambda antikoerper, polymerase (DNA directed), lambda antikoerper, polymerase (DNA) lambda antikoerper, Pol{lambda} antikoerper, PTRG_00468 antikoerper, poll antikoerper, POLL antikoerper, MCYG_03796 antikoerper, LOC9325878 antikoerper, MGYG_02138 antikoerper, Poll antikoerper
- Hintergrund
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Synonyms: BETA N, BETAN, DNA directed DNA polymerase lambda, DNA polymerase beta 2, DNA polymerase beta-2, DNA polymerase kappa, DNA polymerase kappa DNA polymerase beta N, DNA polymerase lambda, DNA polymerase lamda2, DPOLL_HUMAN, EC 2.7.7.7,EC 4.2.99., FLJ46002, OTTHUMP00000020321, OTTHUMP00000020323, OTTHUMP00000059179, Pol beta2, POL KAPPA, Pol Lambda, POLKAPPA, POLL, Polymerase DNA directed lambda.
Background: DNA polymerase lambda (pol lambda), also designated DNA polymerase lambda or Pol Beta2, is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. Encoded by the POLL gene, pol lambda is a member of the DNA polymerase type-X family. Pol lambda extends primer-terminal mispairs opposite nondamaged DNA templates, suggesting that it may assist in extending mismatched base pairs during normal DNA replication. In addition, pol ?may play a role in the mutagenic bypass of T-T dimers. Proliferating cell nuclear antigen (PCNA), a protein essential to DNA replication, interacts with pol lambda and thus influences the ability of pol ?to synthesize DNA.
- Gen-ID
- 27343
- Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
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