PBX3 Antikörper (AA 65-130)
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- Target Alle PBX3 Antikörper anzeigen
- PBX3 (Pre-B-Cell Leukemia Transcription Factor 3 (PBX3))
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Bindungsspezifität
- AA 65-130
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PBX3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PBX3
- Isotyp
- IgG
- Top Product
- Discover our top product PBX3 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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High level of homeobox A9 and PBX homeobox 3 expression in gastric cancer correlates with poor prognosis." in: Oncology letters, Vol. 14, Issue 5, pp. 5883-5889, (2017) (PubMed).
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High level of homeobox A9 and PBX homeobox 3 expression in gastric cancer correlates with poor prognosis." in: Oncology letters, Vol. 14, Issue 5, pp. 5883-5889, (2017) (PubMed).
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- Target
- PBX3 (Pre-B-Cell Leukemia Transcription Factor 3 (PBX3))
- Andere Bezeichnung
- PBX3 (PBX3 Produkte)
- Synonyme
- Pbx3b antikoerper, pre B cell leukemia homeobox 3 antikoerper, PBX homeobox 3 antikoerper, Pbx3 antikoerper, PBX3 antikoerper
- Hintergrund
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Synonyms: Homeobox protein PBX3, MGC134053, OTTHUMP00000064213, Pbx 3, Pbx3, PBX3_HUMAN, Pre B cell leukemia homeobox 3, Pre B cell leukemia transcription factor 3, Pre-B-cell leukemia transcription factor 3, RP11 336P12.1.
Background: Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1,19)(q23,p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92 % and 94 % respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.
- Gen-ID
- 5090
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