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FMR1 Antikörper (pSer500)

FMR1 Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio) WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1714273
  • Target Alle FMR1 Antikörper anzeigen
    FMR1 (Fragile X Mental Retardation 1 (FMR1))
    Bindungsspezifität
    • 14
    • 8
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer500
    Reaktivität
    • 72
    • 52
    • 41
    • 14
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Zebrafisch (Danio rerio)
    Wirt
    • 57
    • 18
    • 2
    Kaninchen
    Klonalität
    • 52
    • 25
    Polyklonal
    Konjugat
    • 44
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FMR1 Antikörper ist unkonjugiert
    Applikation
    • 63
    • 24
    • 18
    • 14
    • 13
    • 12
    • 10
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus, Ratte, Zebrafisch (Danio rerio)
    Homologie
    Dog,Cow,Sheep,Pig,Chicken,Rabbit,Guinea Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human FMRP around the phosphorylation site of Ser500
    Isotyp
    IgG
    Top Product
    Discover our top product FMR1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    FMR1 (Fragile X Mental Retardation 1 (FMR1))
    Andere Bezeichnung
    FMRP (FMR1 Produkte)
    Hintergrund

    Synonyms: POF, FMRP, POF1, FRAXA, Fragile X mental retardation protein 1, Protein FMR-1, FMR1

    Background: Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).

    Gen-ID
    2332
    UniProt
    Q06787
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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