LIMD1 Antikörper (AA 21-120)

Produktnummer ABIN1714317

Produktdetails anti-LIMD1 Antikörper

Target: LIMD1 (LIM Domains Containing 1 (LIMD1))

Bindungsspezifität: AA 21-120

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIMD1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Kreuzreaktivität: Maus

Homologie: Human,Rat,Cow,Sheep,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Limd1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu LIMD1

Target: LIMD1 (LIM Domains Containing 1 (LIMD1))

Andere Bezeichnung: Limd1 (LIMD1 Produkte)

Synonyme: AW822033 antikoerper, D9Ertd192e antikoerper, xlimd1 antikoerper, LIM domains containing 1 antikoerper, LIM domains containing 1 L homeolog antikoerper, LIMD1 antikoerper, Limd1 antikoerper, limd1 antikoerper, limd1.L antikoerper

Hintergrund:

Synonyms: AW822033, D9Ertd192e, LIM domain-containing protein 1, LIM domains containing 1, LIMD1, LIMD1_HUMAN, OTTHUMP00000164657, OTTHUMP00000210317, rCG_25194.

Background: The Zyxin family of proteins contains five members: Ajuba, Limd1, LPP, TRIP6 and Zyxin. Limd1 (LIM domain-containing protein 1) is a ubiquitously expressed tumor suppressor containing 3 LIM zinc-binding domains. LIM domains consist of a cysteine-rich consensus sequence containing two distinct zinc-binding subdomains, which mediate protein-protein interactions. Limd1 interacts with the proteins SQSTM1, Rb, p62 and TRAF6. Limd1 was first identified when the deletion of its gene was noted in some cervical cancers. Limd1 blocks in vitro and in vivo tumor growth and is down-regulated in lung cancer. Limd1 may regulate osteoclast development under stressful conditions via its interactions with TRAF6 and p62.

Gen-ID: 8994

Pathways: Ribonucleoprotein Complex Subunit Organization