FKBP11 Antikörper (AA 121-201)

Produktnummer ABIN1714366

Produktdetails anti-FKBP11 Antikörper

Target: FKBP11 (FK506 Binding Protein 11, 19 KDa (FKBP11))

Bindungsspezifität: AA 121-201

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FKBP11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Homologie: Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FKBP11

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu FKBP11

Target: FKBP11 (FK506 Binding Protein 11, 19 KDa (FKBP11))

Andere Bezeichnung: FKBP11 (FKBP11 Produkte)

Synonyme: MGC85245 antikoerper, 1110002O23Rik antikoerper, FKBP-11 antikoerper, si:dz202l16.2 antikoerper, wu:fd54d02 antikoerper, zgc:110640 antikoerper, FKBP19 antikoerper, FK506 binding protein 11 L homeolog antikoerper, FK506 binding protein 11 antikoerper, fkbp11.L antikoerper, FKBP11 antikoerper, Fkbp11 antikoerper, fkbp11 antikoerper

Hintergrund:

Synonyms: 19 kDa FK506 binding protein, 19 kDa FK506-binding protein, 19 kDa FKBP, FK506 binding protein 11 19 kDa, FK506 binding protein 11, FK506-binding protein 11, FKB11_HUMAN, FKBP 19, FKBP-11, FKBP-19, Fkbp11, FKBP19, MGC54182, Peptidyl prolyl cis trans isomerase, Peptidyl-prolyl cis-trans isomerase FKBP11, PPIase, PPIase FKBP11, Rotamase.

Background: The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs, such as cyclosporin, FK506 and rapamycin. Immunophilins have also been implicated in protein folding and trafficking within the endoplasmic reticulum (ER). FKBP11 (FK506-binding protein 11), also known as FKBP19 or peptidyl-prolyl cis-trans isomerase FKBP11, is a 201 amino acid single-pass membrane protein belonging to the FKBP-type PPIase family, a group of proteins known to catalyze the folding of proline-containing polypeptides. Containing one PPIase FKBP-type domain, FKBP11 is expressed in secretory tissues such as pancreas, pituitary, stomach, lymph node and salivary gland, and is encoded by a gene that maps to human chromosome 12q13.12. FK506 and rapamycin are known to inhibit FKBP11?s peptidyl-prolyl isomerase activity.

Gen-ID: 51303