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CLP1 Antikörper (AA 1-100)

CLP1 Reaktivität: Human WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1714385
  • Target Alle CLP1 Antikörper anzeigen
    CLP1 (Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))
    Bindungsspezifität
    • 14
    • 8
    • 8
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reaktivität
    • 49
    • 12
    • 12
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 45
    • 4
    Kaninchen
    Klonalität
    • 47
    • 2
    Polyklonal
    Konjugat
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CLP1 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 18
    • 12
    • 12
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Cow,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HEAB
    Isotyp
    IgG
    Top Product
    Discover our top product CLP1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CLP1 (Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))
    Andere Bezeichnung
    HEAB (CLP1 Produkte)
    Synonyme
    Heab antikoerper, RGD1307679 antikoerper, AI462438 antikoerper, ACDP1 antikoerper, CLP-1 antikoerper, CGP-39 antikoerper, GP-39 antikoerper, SPC-40 antikoerper, SPS-40 antikoerper, YKL-40 antikoerper, HEAB antikoerper, hClp1 antikoerper, fa28a12 antikoerper, wu:fa28a12 antikoerper, clp1 antikoerper, cleavage and polyadenylation factor I subunit 1 antikoerper, CLP1, cleavage and polyadenylation factor I subunit antikoerper, cyclin and CBS domain divalent metal cation transport mediator 1 antikoerper, chitinase 3-like 1 (cartilage glycoprotein-39) antikoerper, cleavage and polyadenylation factor I subunit 1 L homeolog antikoerper, Clp1 antikoerper, CNNM1 antikoerper, CHI3L1 antikoerper, CLP1 antikoerper, clp1 antikoerper, clp1.L antikoerper
    Hintergrund

    Synonyms: ATP/GTP binding protein, CLP 1, clp1, CLP1 cleavage and polyadenylation factor I subunit homolog, CLP1, cleavage and polyadenylation factor I subunit, homolog S. cerevisiae, CLP1, yeast, homolog of, CLP1_HUMAN, hClp1, Homolog of yeast CFIA subunit Clp1p, Polynucleotide kinase Clp1, Pre mRNA cleavage complex II protein Clp1, Pre-mRNA cleavage complex II protein Clp1.

    Background: HEAB is a 425 amino acid nuclear protein that belongs to the Clp1 family. Utilizing magnesium, manganese or nickel as cofactors, HEAB participates in the phosphorylation of the 5'-hydroxyl groups of double- and single- stranded RNA and DNA. HEAB is a member of the tRNA splicing endonuclease complex, in conjunction with TSEN2, TSEN15, TSEN34 and TSEN54, and is also a member of the pre-mRNA cleavage complex II. The gene encoding HEAB maps to human chromosome 11q12.1 and mouse chromosome 2 D, mutations to this gene may lead to a reduced pre-mRNA cleavage activity. HEAB exists as two isoforms due to alternative splicing events.

    Gen-ID
    10978
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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