CYP1B1 Antikörper (AA 441-543)
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- Target Alle CYP1B1 Antikörper anzeigen
- CYP1B1 (Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1))
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Bindungsspezifität
- AA 441-543
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CYP1B1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Kreuzreaktivität
- Maus
- Homologie
- Human,Rat,Dog,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CYP1B1
- Isotyp
- IgG
- Top Product
- Discover our top product CYP1B1 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CYP1B1 (Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1))
- Andere Bezeichnung
- CYP1B1 (CYP1B1 Produkte)
- Synonyme
- CP1B antikoerper, CYPIB1 antikoerper, GLC3A antikoerper, P4501B1 antikoerper, P4501b1 antikoerper, CYP1B1 antikoerper, CYP1B antikoerper, zgc:136223 antikoerper, cytochrome P450 family 1 subfamily B member 1 antikoerper, cytochrome P450, family 1, subfamily b, polypeptide 1 antikoerper, cytochrome P450, family 1, subfamily B, polypeptide 1 antikoerper, cytochrome P450 1B1 antikoerper, CYP1B1 antikoerper, Cyp1b1 antikoerper, cyp1b1 antikoerper, LOC100719054 antikoerper
- Hintergrund
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Synonyms: CP1B, GLC3A, CYPIB1, P4501B1, Cytochrome P450 1B1, CYP1B1
Background: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, retinoid and xenobiotics. Preferentially oxidizes 17beta-estradiol to the carcinogenic 4-hydroxy derivative, and a variety of procarcinogenic compounds to their activated forms, including polycyclic aromatic hydrocarbons. Promotes angiogenesis by removing cellular oxygenation products, thereby decreasing oxidative stress, release of antiangiogenic factor THBS2, then allowing endothelial cells migration, cell adhesion and capillary morphogenesis. These changes are concommitant with the endothelial nitric oxide synthase activity and nitric oxide synthesis. Plays an important role in the regulation of perivascular cell proliferation, migration, and survival through modulation of the intracellular oxidative state and NF-kappa-B expression and/or activity, during angiogenesis. Contributes to oxidative homeostasis and ultrastructural organization and function of trabecular meshwork tissue through modulation of POSTN expression.
- Gen-ID
- 1545
- UniProt
- Q16678
- Pathways
- Steroid Hormone Biosynthesis
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