ADRM1 Antikörper (AA 21-120)

Produktnummer ABIN1714487

Produktdetails anti-ADRM1 Antikörper

Target: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Bindungsspezifität: AA 21-120

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADRM1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ADRM1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ADRM1

Target: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Andere Bezeichnung: ADRM1 (Adrm1 Produkte)

Synonyme: arm-1 antikoerper, gp110 antikoerper, rpn13 antikoerper, xoom antikoerper, ADRM1 antikoerper, adrm1 antikoerper, ARM-1 antikoerper, ARM1 antikoerper, GP110 antikoerper, 1110063P18Rik antikoerper, 2510006J17Rik antikoerper, AA408205 antikoerper, AU043535 antikoerper, Arm1 antikoerper, Gp110 antikoerper, Rpn13 antikoerper, adrm1a antikoerper, adrm1b antikoerper, fa12d09 antikoerper, wu:fa10g10 antikoerper, wu:fa12d09 antikoerper, zgc:56107 antikoerper, zgc:77256 antikoerper, adhesion regulating molecule 1 antikoerper, ADRM1 antikoerper, 19S proteasome regulatory subunit antikoerper, ADRM1 protein antikoerper, adrm1 antikoerper, ADRM1 antikoerper, CpipJ_CPIJ002929 antikoerper, SJAG_04211 antikoerper, Adrm1 antikoerper

Hintergrund:

Synonyms: 110 kDa cell membrane glycoprotein, adhesion regulating molecule 1, Adhesion-regulating molecule 1, ADRM 1, Adrm1, ADRM1_HUMAN, ARM 1, ARM-1, ARM1, GP110, hRpn13, Mr 110,000 surface antigen, Proteasomal ubiquitin receptor ADRM1, proteasome regulatory particle non ATPase 13, Proteasome regulatory particle non-ATPase 13, Regulatory particle non ATPase 13, Rpn13, Rpn13 homolog.

Background: ADRM1 is a 407 amino acid protein that localizes to both the nucleus and the cytoplasm and is thought to be involved in protein recruitment and cell adhesion. An integral membrane protein, ADRM1 functions to recruit UCH-L5, a deubiquitinating enzyme, to the 26S proteasome, and once at the proteasome it promotes the activity of UCH-L5. Additionally, ADRM1 is thought to mediate lymphocyte adhesion in endothelial cells and may thus play a role in lymphocyte homing. ADRM1 expression is induced by IFN-g in some cancer cell lines and its expression is upregulated in other metastatic cells, suggesting a role in carcinogenesis. Two isoforms of ADRM1 exist due to alternative splicing events.

Gen-ID: 11047

Pathways: Positive Regulation of Endopeptidase Activity