BAMBI Antikörper (AA 101-200)

Produktnummer ABIN1714490

Produktdetails anti-BAMBI Antikörper

Target: BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))

Bindungsspezifität: AA 101-200

Reaktivität: Human, Ratte, Maus, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAMBI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Schwein, Ratte

Homologie: Dog,Cow,Sheep,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BAMBI

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-BAMBI Antikörper (ABIN1714490)

He, Ou, Chen, Zu, Liu, Li, Cao, Chen, Chen, Chen, Qi, Wang: "LPS/TLR4 Signaling Enhances TGF-β Response Through Downregulating BAMBI During Prostatic Hyperplasia." in: Scientific reports, Vol. 6, pp. 27051, (2016) (PubMed).

Du, Niu, Wang, Zhao, Kong, Zhang, Nan: "TLR4‑dependent signaling pathway modulation: A novel mechanism by which pioglitazone protects against nutritional fibrotic steatohepatitis in mice." in: Molecular medicine reports, Vol. 13, Issue 3, pp. 2159-66, (2016) (PubMed).

Bai, Chu, Mai, Zheng, Wang, Zhang, Yang: "Identification and expression analyses of BAMBI mediated by FSH in swine luteinizing granulosa cells." in: Theriogenology, Vol. 82, Issue 8, pp. 1094-101, (2014) (PubMed).

Details zu BAMBI

Target: BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))

Andere Bezeichnung: BAMBI (BAMBI Produkte)

Synonyme: NMA antikoerper, bambi antikoerper, nma antikoerper, BAMBI antikoerper, Zfnma antikoerper, cb998 antikoerper, fc44c12 antikoerper, id:ibd5020 antikoerper, wu:fc44c12 antikoerper, wu:fe01e03 antikoerper, 2610003H06Rik antikoerper, bambi-A antikoerper, zgc:91871 antikoerper, BMP and activin membrane bound inhibitor antikoerper, BMP and activin membrane-bound inhibitor homolog antikoerper, BMP and activin membrane-bound inhibitor antikoerper, BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a antikoerper, BMP and activin membrane-bound inhibitor L homeolog antikoerper, BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b antikoerper, BAMBI antikoerper, bambi antikoerper, bambia antikoerper, Bambi antikoerper, LOC724378 antikoerper, LOC100647353 antikoerper, bambi.L antikoerper, bambib antikoerper

Hintergrund:

Synonyms: NMA, BMP and activin membrane-bound inhibitor homolog, Non-metastatic gene A protein, Putative transmembrane protein NMA, BAMBI

Background: BAMBI is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development. The BAMBI family of proteins are related to type I TGF-beta receptor family, however, BAMBI is a pseudoreceptor that lacks an intracellular serine/threonine kinase domain. BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4. BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues. BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines.

Gen-ID: 25805

UniProt: Q13145