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CXCR4 Antikörper (pSer339)

CXCR4 Reaktivität: Human, Maus WB, ELISA, FACS, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1714582
  • Target Alle CXCR4 Antikörper anzeigen
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    Bindungsspezifität
    • 18
    • 15
    • 15
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer339
    Reaktivität
    • 140
    • 89
    • 66
    • 21
    • 11
    • 11
    • 10
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 112
    • 30
    • 12
    • 10
    • 1
    Kaninchen
    Klonalität
    • 120
    • 45
    Polyklonal
    Konjugat
    • 99
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CXCR4 Antikörper ist unkonjugiert
    Applikation
    • 112
    • 57
    • 52
    • 38
    • 27
    • 26
    • 25
    • 25
    • 20
    • 11
    • 9
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Dog,Cow,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human CXCR4 around the phosphorylation site of Ser339 [HS(p-S)VS]
    Isotyp
    IgG
    Top Product
    Discover our top product CXCR4 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    Andere Bezeichnung
    CXCR4 (CXCR4 Produkte)
    Hintergrund

    Synonyms: p-CXCR4 phospho S339, p-CD184 phospho S339, C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, Stromal cell-derived factor 1 receptor, SDF-1 receptor, Fusin, Leukocyte-derived seven transmembrane domain receptor, LESTR, CD184 antigen, CXCR4_HUMAN.

    Background: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Monomer. Can form dimers.

    Gen-ID
    55038
    Pathways
    Regulation of Cell Size, CXCR4-mediated Signaling Events
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