AGO2 Antikörper (AA 431-530)

Produktnummer ABIN1714738

Produktdetails anti-AGO2 Antikörper

Target: AGO2 (Argonaute 2 (AGO2))

Bindungsspezifität: AA 431-530

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AGO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human eIF2C2/Ago2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu AGO2

Target: AGO2 (Argonaute 2 (AGO2))

Andere Bezeichnung: e2C2/Ago2 (AGO2 Produkte)

Synonyme: EIF2C2 antikoerper, T19E23.7 antikoerper, T19E23_7 antikoerper, argonaute 2 antikoerper, Q10 antikoerper, Eif2c2 antikoerper, Argonaute2 antikoerper, eif2c1 antikoerper, eif2c2 antikoerper, 1110029L17Rik antikoerper, 2310051F07Rik antikoerper, AI225898 antikoerper, AL022874 antikoerper, AW546247 antikoerper, ENSMUSG00000072493 antikoerper, Gerp95 antikoerper, Gm10365 antikoerper, mKIAA4215 antikoerper, AGO2 antikoerper, AG02 antikoerper, AGO 2 antikoerper, Ago-2 antikoerper, Ago2 antikoerper, CG13452 antikoerper, CG7439 antikoerper, Dm Ago2 antikoerper, Dmel\\CG7439 antikoerper, ago antikoerper, ago-2 antikoerper, ago2 antikoerper, dAGO2 antikoerper, dAgo2 antikoerper, eIF2C2 antikoerper, argonaute 2, RISC catalytic component antikoerper, Argonaute family protein antikoerper, argonaute 2, RISC catalytic component L homeolog antikoerper, argonaute RISC catalytic subunit 2 antikoerper, argonaute RISC catalytic component 2 antikoerper, Argonaute 2 antikoerper, AGO2 antikoerper, Ago2 antikoerper, ago2.L antikoerper, ago2 antikoerper

Hintergrund:

Synonyms: Ago 2, AGO2_HUMAN, Argonaute 2, Argonaute2, dAgo2, e 2C 2, e-2C 2, e2C 2, E2c2, Eukaryotic translation initiation factor 2C 2, hAgo2, MGC3183, PAZ Piwi domain protein, PPD, Protein argonaute-2, Protein slicer, Q10, Slicer protein.

Background: Eukaryotic translation initiation factor 2C (eIF2C) proteins (argonaute family) influence RNA interference (RNAi) as components of the RNA-inducible silencing complex (RISC) or microRNA (miRNA)-containing ribonucleoprotein particle (miRNP). Small RNAs, including small interfering RNAs (siRNAs) and miRNAs, can silence target genes through mechanisms that utilize RISC or miRNP particles. eIF2C1 (argonaute 1, AGO1, eIF2C, GERP95, Q99) and Dicer1 play a coordinated role in siRNA-mediated gene silencing. eIF2C2 (Slicer, argonaute 2, AGO2, Q10) is a RISC component that can concentrate in cytoplasmic processing bodies (P-bodies) and catalyze mRNA cleavage. Mammalian P-bodies contain mRNAs and have an association with miRNA-induced translational silencing and siRNA-induced mRNA degradation. Additional eIF2C proteins include eIF2C3 (argonaute 3, AGO3), eIF2C4 (argonaute 4, AGO4) and meIF2c5 (mouse argonaute 5).

Gen-ID: 27161

UniProt: Q9UKV8

Pathways: Fc-epsilon Rezeptor Signalübertragung, Regulatorische RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Ribonucleoprotein Complex Subunit Organization