IGFBPL1 Antikörper (AA 201-278)
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- Target Alle IGFBPL1 Produkte
- IGFBPL1 (Insulin-Like Growth Factor Binding Protein-Like 1 (IGFBPL1))
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Bindungsspezifität
- AA 201-278
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IGFBPL1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human IGFBPL1
- Isotyp
- IgG
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- Applikationshinweise
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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Epigenetic silencing of IGFBPL1 promotes esophageal cancer growth by activating PI3K-AKT signaling." in: Clinical epigenetics, Vol. 12, Issue 1, pp. 22, (2021) (PubMed).
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Epigenetic silencing of IGFBPL1 promotes esophageal cancer growth by activating PI3K-AKT signaling." in: Clinical epigenetics, Vol. 12, Issue 1, pp. 22, (2021) (PubMed).
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- Target
- IGFBPL1 (Insulin-Like Growth Factor Binding Protein-Like 1 (IGFBPL1))
- Andere Bezeichnung
- IGFBPL1 (IGFBPL1 Produkte)
- Synonyme
- IGFBP-RP4 antikoerper, IGFBPRP4 antikoerper, bA113O24.1 antikoerper, 2810011G06Rik antikoerper, 2810453O06Rik antikoerper, IGFBPL antikoerper, insulin like growth factor binding protein like 1 antikoerper, insulin-like growth factor binding protein-like 1 antikoerper, IGFBPL1 antikoerper, Igfbpl1 antikoerper
- Hintergrund
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Synonyms: bA113O24.1, IGFBP-related protein 10, IGFBP-RP4, IGFBPRP4, insulin-like growth factor binding protein related protein 4, insulin-like growth factor-binding protein-like 1, IBPL1_HUMAN, insulin-like growth factor-binding-related protein 4.
Background: IGFBPL1 is a secreted IGF (Insulin-like growth factor) binding protein that is known to contain an Ig-like C2-type (immunoglobulin-like) domain, an IGFBP N-terminal domain and a Kazal-like domain. IGF-binding proteins characteristically act to extend the half-life of IGFs and may influence the growth promoting effects of the IGFs. The interaction of IGFBPs with IGFs can affect cell surface receptors, specifically, IGFBPs may enhance or decrease a cells insulin sensitivity. IGFBPL1 has been found to be down-regulated in multiple tumors and thus may be a likely tumor suppressor candidate. Highly expressed in both brain and testis, IGFBPL1 is found at lower levels in the prostate, bladder and lung.
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