SNX9 Antikörper (AA 501-595)

Produktnummer ABIN1714873

Produktdetails anti-SNX9 Antikörper

Target: SNX9 (Sorting Nexin 9 (SNX9))

Bindungsspezifität: AA 501-595

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNX9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SNX9

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu SNX9

Target: SNX9 (Sorting Nexin 9 (SNX9))

Andere Bezeichnung: SNX9/SH3PX1 (SNX9 Produkte)

Synonyme: si:bz36d5.4 antikoerper, snx9 antikoerper, zgc:113455 antikoerper, MGC78823 antikoerper, SNX9 antikoerper, SDP1 antikoerper, SH3PX1 antikoerper, SH3PXD3A antikoerper, WISP antikoerper, 2700073N08Rik antikoerper, sorting nexin 9a antikoerper, sorting nexin 9 antikoerper, sorting nexin 9 L homeolog antikoerper, snx9a antikoerper, SNX9 antikoerper, snx9.L antikoerper, snx9 antikoerper, Snx9 antikoerper

Hintergrund:

Synonyms: SDP1, WISP, SH3PX1, SH3PXD3A, Sorting nexin-9, SH3 and PX domain-containing protein 1, Protein SDP1, SH3 and PX domain-containing protein 3A, SNX9

Background: Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates the GTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate.

Gen-ID: 51429

UniProt: Q9Y5X1