UBE2Z Antikörper (AA 151-259)

Produktnummer ABIN1714891

Produktdetails anti-UBE2Z Antikörper

Target: UBE2Z (Ubiquitin-Conjugating Enzyme E2Z (UBE2Z))

Bindungsspezifität: AA 151-259

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2Z Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human USE1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu UBE2Z

Target: UBE2Z (Ubiquitin-Conjugating Enzyme E2Z (UBE2Z))

Andere Bezeichnung: USE1 (UBE2Z Produkte)

Hintergrund:

Synonyms: 2010315L10Rik, 5730403H22Rik, AV002165, D12, Ed2, Embryonic development factor 2, MDS032, P31, Protein D12, Protein p31, putative MAPK activating protein PM26, Putative MAPK-activating protein PM26, Q-snare, RGD1306660, SLT1, SNARE-like tail-anchored protein 1 homolog, Unconventional SNARE in the ER 1 homolog S. cerevisiae, Unconventional SNARE in the ER 1 homolog, Use1, USE1 like protein, Use1 unconventional SNARE in the ER 1 homolog S. cerevisiae, USE1-like protein, USE1_HUMAN, USE1L, Vesicle transport protein USE1.

Background: In eukaryotic cells, the Golgi apparatus receives newly synthesized proteins from the endoplasmic reticulum (ER) and, after covalent modification, delivers them to their destination in the cell. For membrane-directed proteins this process is believed to be carried out via vesicular transport. Correct vesicular transport is determined by specific pairing of vesicle-associated SNAREs (v-SNAREs) with those on the target membrane (t-SNAREs). Unconventional SNARE in the ER 1, also known as USE1 or protein p31, is a 259 amino acid t-SNARE that forms a larger complex with ZW10, RINT-1 and Syntaxin 18. Upon Mg2+-AP treatment in the presence of NSF and ?SNAP, ZW10, RINT-1 and USE1 dissociate from Syntaxin 18. USE1 is a single-pass type IV membrane protein that is localized to the endoplasmic reticulum membrane. Three named isoforms exist for USE1 as a result of alternative splicing events.

Gen-ID: 55850