GDI1 Antikörper (AA 1-100)

Produktnummer ABIN1715018

Produktdetails anti-GDI1 Antikörper

Target: GDI1 (GDP Dissociation Inhibitor 1 (GDI1))

Bindungsspezifität: AA 1-100

Reaktivität: Maus, Schimpanse

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GDI1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Schimpanse, Maus

Homologie: Human,Rat,Cow,Sheep,Pig,Rabbit,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GDI1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-GDI1 Antikörper (ABIN1715018)

Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

Details zu GDI1

Target: GDI1 (GDP Dissociation Inhibitor 1 (GDI1))

Andere Bezeichnung: GDI1 (GDI1 Produkte)

Synonyme: 1A antikoerper, GDIL antikoerper, MRX41 antikoerper, MRX48 antikoerper, OPHN2 antikoerper, RABGD1A antikoerper, RABGDIA antikoerper, XAP-4 antikoerper, GDIA antikoerper, GDIalpha antikoerper, GDI-1 antikoerper, zgc:110600 antikoerper, QccE-14779 antikoerper, Rab GDI alpha antikoerper, GDP dissociation inhibitor 1 antikoerper, GDP dissociation inhibitor 1 S homeolog antikoerper, guanosine diphosphate (GDP) dissociation inhibitor 1 antikoerper, GDI1 antikoerper, gdi1.S antikoerper, Gdi1 antikoerper, gdi1 antikoerper

Hintergrund:

Synonyms: 1A, FLJ41411, GDI-1, gdi1, GDIA_HUMAN, GDIL, GDP dissociation inhibitor 1, Guanosine diphosphate dissociation inhibitor 1, Mental retardation X-linked 41, Mental retardation X-linked 48, MRX41, MRX48, Oligophrenin 2, Oligophrenin-2, OPHN2, Protein XAP 4, Protein XAP-4, Protein XAP4, Rab GDI alpha, Rab GDP dissociation inhibitor alpha, RABGD1A, RABGDIA, XAP 4.

Background: Rab proteins, a family of Ras-related small GTP-binding proteins, play a key role in regulating intracellular vesicle trafficking (1?). Rab GDP dissociation inhibitor (Rab GDI or GDI2) forms a soluble complex with Rab proteins and thereby prevents the exchange of GDP for GTP (1?). In mammals, there exist two major isoforms, Rab GDI alpha (also known as XAP-4) and Rab GDI beta (1,4). While the mammalian Rab GDI beta-genes are ubiquitously expressed, the Rab GDI ?genes are predominantly brain-specific (1). Since it is expressed predominantly in neural and sensory tissues, Rab GDI a may serve a specific function in neural signal transmission (5). The gene sequences for the Rab GDI proteins are extremely conserved in evolution, with substantial homology preserved across three eukaryotic kingdoms (5).

Gen-ID: 2664