GMPPB Antikörper (AA 111-210)

Produktnummer ABIN1715025

Produktdetails anti-GMPPB Antikörper

Target: GMPPB (GDP-Mannose Pyrophosphorylase B (GMPPB))

Bindungsspezifität: AA 111-210

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GMPPB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GMPPB

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu GMPPB

Target: GMPPB (GDP-Mannose Pyrophosphorylase B (GMPPB))

Andere Bezeichnung: GMPPB (GMPPB Produkte)

Synonyme: MDDGA14 antikoerper, MDDGB14 antikoerper, MDDGC14 antikoerper, AI317178 antikoerper, E430010H19 antikoerper, RGD1560458 antikoerper, gmppl antikoerper, zgc:92026 antikoerper, GMPPB antikoerper, gmppb antikoerper, gmppb-a antikoerper, gmppb-b antikoerper, GDP-mannose pyrophosphorylase B antikoerper, GDP-mannose pyrophosphorylase B L homeolog antikoerper, GDP-mannose pyrophosphorylase B S homeolog antikoerper, GMPPB antikoerper, Gmppb antikoerper, gmppb antikoerper, LOAG_13550 antikoerper, gmppb.L antikoerper, gmppb.S antikoerper

Hintergrund:

Synonyms: GDP mannose pyrophosphorylase B, GDP-mannose pyrophosphorylase B, GMPPB, GMPPB_HUMAN, GTP-mannose-1-phosphate guanylyltransferase beta, KIAA1851, Mannose 1 phosphate guanylyltransferase, Mannose-1-phosphate guanyltransferase beta.

Background: GMPPB is a 360 amino acid protein that belongs to the transferase hexapeptide repeat family and is involved in protein modification pathways. Functioning as a GDP-mannose pyrophosphorylase, GMPPB enzymatically catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose and a free phosphate, a reaction that is involved in the production of N-linked oligosaccharides. Defects in the gene encoding GMPPB that cause errors in the glycosylation pathway may lead to congenital disorders of glycosylation (CDG). CDGs are multisystemic diseases that often involve both the central and peripheral nervous systems and are often characterized by endocrine and coagulation disorders. GMPPB is expressed as two isoforms due to alternative splicing events.

Gen-ID: 29925