VPREB1 Antikörper (AA 61-145)

Produktnummer ABIN1715058

Produktdetails anti-VPREB1 Antikörper

Target: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Bindungsspezifität: AA 61-145

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VPREB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VPREB1/CD179a

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu VPREB1

Target: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Andere Bezeichnung: VPREB1/CD179a (VPREB1 Produkte)

Synonyme: IGI antikoerper, IGVPB antikoerper, VPREB antikoerper, VpreB antikoerper, CD179a antikoerper, Vpreb-1 antikoerper, V-set pre-B cell surrogate light chain 1 antikoerper, immunoglobulin iota chain antikoerper, immunoglobulin iota chain-like antikoerper, pre-B lymphocyte 1 antikoerper, pre-B lymphocyte gene 1 antikoerper, VPREB1 antikoerper, LOC698810 antikoerper, LOC486411 antikoerper, Vpreb1 antikoerper

Hintergrund:

Synonyms: CD179 antigen like family member A, CD179 antigen-like family member A, CD179a, IGI, IGVPB, Immunoglobulin iota chain, Pre B lymphocyte 1, pre-B lymphocyte 1, Protein VPreB1, VpreB protein, VPREB 1, VPREB, VpreB protein, VPREB_HUMAN, VPREB1.

Background: VpreB is expressed in pre-B lymphocytes, but not in mature B cells or in other blood cell lineages. The gene which encodes VpreB maps to human chromosome 22q11.2. The VpreB and Lambda 5 genes encode the Iota and Omega polypeptide chains, respectively, which associate with the Ig-Mu chain to form a molecular complex that is expressed on the surface of pre-B cells. This complex presumably regulates Ig gene rearrangements in the early steps of B cell differentiation. In the mouse the two genes are simultaneously expressed in pre-B cells and belong to the same transcription unit. A primary transcript is synthesized from which the pre-B and Lambda 5 mRNAs are derived by alternative splicing. In the human, however, the two genes are separate and do not belong to the same transcription unit.

Gen-ID: 7441

Pathways: Production of Molecular Mediator of Immune Response, Regulation of Cell Size