CD81 Antikörper
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- Target Alle CD81 Antikörper anzeigen
- CD81
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Reaktivität
- Human
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD81 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Cell-ELISA (cELISA)
- Spezifität
- Anti-human CD81 (TAPA-1)
- Produktmerkmale
- Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
- Aufreinigung
- Protein G
- Immunogen
- genetic immunisation with cDNA encoding human CD81
- Klon
- QV-6A8-S3
- Isotyp
- IgG2b
- Top Product
- Discover our top product CD81 Primärantikörper
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- Applikationshinweise
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Flow cytometry: 1.2 µg/10^6 cells
ELISA: 1:200 - 1:400
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - Kommentare
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Synonyms: TAPA-1
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS, pH 7.2
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- short term: 2 °C - 8 °C, long term: -20 °C
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A novel monoclonal anti-CD81 antibody produced by genetic immunization efficiently inhibits Hepatitis C virus cell-cell transmission." in: PLoS ONE, Vol. 8, Issue 5, pp. e64221, (2013) (PubMed).
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A novel monoclonal anti-CD81 antibody produced by genetic immunization efficiently inhibits Hepatitis C virus cell-cell transmission." in: PLoS ONE, Vol. 8, Issue 5, pp. e64221, (2013) (PubMed).
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- Target
- CD81
- Andere Bezeichnung
- CD81 (CD81 Produkte)
- Synonyme
- Tapa-1 antikoerper, Tapa1 antikoerper, Tspan28 antikoerper, CVID6 antikoerper, S5.7 antikoerper, TAPA1 antikoerper, TSPAN28 antikoerper, CD81 molecule antikoerper, CD81 molecule b antikoerper, CD81 antigen antikoerper, Cd81 molecule antikoerper, CD81 antikoerper, cd81b antikoerper, Cd81 antikoerper
- Hintergrund
- CD81 (TAPA-1) belongs to the transmembrane 4 superfamily (tetraspanin family). CD81 is a widely expressed cell-surface protein that is characterized by the presence of four transmembranic domains, short N and C termini, a small extracellular loop (SEL) and a large extra-cellular loop (LEL). It is expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin and plays a role in the regulation of cell development, cell-growth and signal transduction. CD81 plays a critical role in Hepatitis C Infection and is involved in HCV entry due to its ability to interact with virus' E1/E2 glycoproteins. CD81 is an essential HCV host factor as silencing of CD81 expression by CD81-specific monoclonal antibodies in hepatoma cells inhibits HCV entry.
- UniProt
- P60033
- Pathways
- Inositol Metabolic Process, Hepatitis C
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