Claudin 6/9 Antikörper

Produktnummer ABIN1720918

Produktdetails

Target: Claudin 6/9

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Applikation: Cell-ELISA (cELISA), Flow Cytometry (FACS)

Spezifität: Anti-human Claudin 6 and Claudin 9

Produktmerkmale: Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells

Aufreinigung: Protein G

Immunogen: genetic immunisation with cDNA encoding human Claudin 9

Klon: YD-9H8

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 1.2 µg/10^6 cells
ELISA: 1:200 - 1:400
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.

Kommentare:

Synonyms: CLDN6, CLDN9

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.2

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C

Informationen zur Lagerung: short term: 2 °C - 8 °C, long term: -20 °C

Referenzen

Fofana, Zona, Thumann, Heydmann, Durand, Lupberger, Blum, Pessaux, Gondeau, Reynolds, McKeating, Grunert, Thompson, Zeisel, Baumert: "Functional analysis of claudin-6 and claudin-9 as entry factors for hepatitis C virus infection of human hepatocytes by using monoclonal antibodies." in: Journal of virology, Vol. 87, Issue 18, pp. 10405-10, (2013) (PubMed).

Antigendetails

Target: Claudin 6/9

Hintergrund: Claudin 6 and 9 play a major role in tight junction-specific obliteration of the intercellular space. Claudin 6 and Claudin 9 have been reported to mediate HCV entry

UniProt: P19235, O95484