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p53 Antikörper

TP53 Reaktivität: Human ELISA (Capture) Wirt: Maus Monoclonal B-F34 unconjugated
Produktnummer ABIN1722440
  • Target Alle p53 (TP53) Antikörper anzeigen
    p53 (TP53) (Tumor Protein P53 (TP53))
    Reaktivität
    • 834
    • 255
    • 211
    • 107
    • 50
    • 34
    • 33
    • 19
    • 10
    • 9
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 623
    • 228
    • 6
    • 2
    • 1
    Maus
    Klonalität
    • 559
    • 300
    • 1
    Monoklonal
    Konjugat
    • 484
    • 38
    • 32
    • 19
    • 19
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 12
    • 12
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser p53 Antikörper ist unkonjugiert
    Applikation
    • 668
    • 298
    • 250
    • 202
    • 200
    • 149
    • 128
    • 124
    • 119
    • 68
    • 59
    • 35
    • 18
    • 16
    • 13
    • 12
    • 9
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA (Capture)
    Spezifität
    Reacts with wild type and mutant p53, the epitope is within residues 18-30 of human p53
    Aufreinigung
    Purified
    Immunogen
    Recombinant p53 protein
    Klon
    B-F34
    Isotyp
    IgG2b
    Top Product
    Discover our top product TP53 Primärantikörper
  • Applikationshinweise

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    ELISA-C1 - 5 μg/mL

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    PBS, Sterile-filtered through 0.22 μm Carrier and Preservative free
    Konservierungsmittel
    Without preservative
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.
    Haltbarkeit
    6 months
  • Target
    p53 (TP53) (Tumor Protein P53 (TP53))
    Andere Bezeichnung
    p53 (TP53 Produkte)
    Hintergrund
    Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis, the function is largely independent of transcription.
    Gen-ID
    7157
    UniProt
    P04637
    Pathways
    p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie, Warburg Effekt
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