Tacrolimus (FK506) Antikörper
FK506
Reaktivität: Chemical
ELISA, WB
Wirt: Maus
Monoclonal
FK1
unconjugated
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- Target
- Tacrolimus (FK506)
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Reaktivität
- Chemical
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Unkonjugiert
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Applikation
- ELISA, Western Blotting (WB)
- Spezifität
- Reacts with conjugated and non-conjugated FK-506 (Kd=10E-9M)
- Aufreinigung
- Purified
- Immunogen
- FK-506 conjugated to bovine serum albumin.
- Klon
- FK1
- Isotyp
- IgM
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- Applikationshinweise
- Working dilution: Optimal dilution should be determined by the end user.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Dilute in PBS or medium which is identical to that used in the assay system.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Tacrolimus (FK506)
- Andere Bezeichnung
- FK-506
- Substanzklasse
- Chemical
- Hintergrund
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FK-506 is a novel macrolide with similar, but more potent, immunosuppressant activity than cyclosporine. FK-506 is used for primary or rescue immunosuppression in patients after solid organ transplantation. Clinically relevant side effects of FK-506 administration are nephrotoxicity, neurotoxicity, diabetes mellitus, and hypertension. Most of these side effects are related to blood levels of FK-506 rather than dosage. Therefore, therapeutic drug monitoring of FK-506 is a prerequisite for therapy. The whole blood target level range aimed for in clinical practice is 3.0-20.0 ng/mL and depends on the patient's liver function, the nature of organ transplantation, and the time after transplantation.
Tacrolimus Fujimycin CAS : 109581-93-3 C44H69NO12 . H2O
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