MSH2 Antikörper
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- Target Alle MSH2 Antikörper anzeigen
- MSH2 (Mismatch Repair Protein 2 (MSH2))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser MSH2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- Verwendungszweck
- MSH2 Antibody
- Aufreinigung
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human MSH2 expressed in E. Coli.
- Klon
- 1B3A8A8
- Isotyp
- IgG1
- Top Product
- Discover our top product MSH2 Primärantikörper
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anti-Mismatch Repair Protein 2 (MSH2) (AA 442-586) antibody
MSH2 Reaktivität: Human WB, ELISA, IHC, FACS, ICC Wirt: Maus Monoclonal 2E2C7 unconjugated
anti-Mismatch Repair Protein 2 (MSH2) (AA 327-427) antibodyMSH2 Reaktivität: Human WB, IHC, FACS, StM Wirt: Maus Monoclonal MSH2-2622 unconjugated
anti-Mismatch Repair Protein 2 (MSH2) (AA 1-300) antibodyMSH2 Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Mismatch Repair Protein 2 (MSH2) (AA 1-934) antibodyMSH2 Reaktivität: Human WB, IF, PLA Wirt: Kaninchen Polyclonal unconjugated
anti-Mismatch Repair Protein 2 (MSH2) (AA 337-583) antibodyMSH2 Reaktivität: Human, Maus, Ratte WB, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Mismatch Repair Protein 2 (MSH2) (AA 835-934) antibodyMSH2 Reaktivität: Human WB, ELISA, PLA Wirt: Maus Monoclonal 4B2 unconjugated
anti-Mismatch Repair Protein 2 (MSH2) (AA 442-586) antibodyMSH2 Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 4F10D6 unconjugated
anti-Mismatch Repair Protein 2 (MSH2) (AA 224-313) antibodyMSH2 Reaktivität: Human IHC, StM Wirt: Maus Monoclonal SYP-3551 unconjugated
anti-Mismatch Repair Protein 2 (MSH2) (AA 637-665) antibodyMSH2 Reaktivität: Human WB, ELISA, IF, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Mismatch Repair Protein 2 (MSH2) (AA 2-254) antibodyMSH2 Reaktivität: Human WB, ELISA, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- MSH2 (Mismatch Repair Protein 2 (MSH2))
- Andere Bezeichnung
- MSH2 (MSH2 Produkte)
- Hintergrund
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Description: MSH2 is a 100 kDa nuclear antigen and encodes a protein of 934 amino acids. The MSH2 gene is one of 4 known genes encoding proteins involved in the repair of mismatch nucleotides following DNA
replication or repair. Mutations in the MSH2 gene contribute to the development of sporadic
colorectal carcinoma. MSHS mutations are responsible for 50 % of inherited non-polyposis colorectal
(HNPCC). The repair of mismatch DNA is essential to maintaining the integrity of genetic
information over time. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI).
These defects in DNA repair pathways have been related to human carcinogenesis. MSH-2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process.Aliases: FCC1, COCA1, HNPCC, LCFS2
- Molekulargewicht
- 105kDa
- Gen-ID
- 4436
- HGNC
- 4436
- UniProt
- P43246
- Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
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