Ret Proto-Oncogene Antikörper (AA 896-1063)
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- Target Alle Ret Proto-Oncogene (RET) Antikörper anzeigen
- Ret Proto-Oncogene (RET)
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Bindungsspezifität
- AA 896-1063
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Ret Proto-Oncogene Antikörper ist unkonjugiert
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Applikation
- ELISA
- Verwendungszweck
- RET Antibody
- Aufreinigung
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of RET (aa896-1063) expressed in E. Coli.
- Klon
- 8D10C9
- Isotyp
- IgG1
- Top Product
- Discover our top product RET Primärantikörper
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- Applikationshinweise
- ELISA: 1/10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Guidance cues involved in the development of the peripheral autonomic nervous system." in: Autonomic neuroscience : basic & clinical, Vol. 112, Issue 1-2, pp. 1-14, (2004) (PubMed).
: "The RET receptor is linked to stress response pathways." in: Cancer research, Vol. 64, Issue 13, pp. 4453-63, (2004) (PubMed).
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Guidance cues involved in the development of the peripheral autonomic nervous system." in: Autonomic neuroscience : basic & clinical, Vol. 112, Issue 1-2, pp. 1-14, (2004) (PubMed).
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- Target
- Ret Proto-Oncogene (RET)
- Andere Bezeichnung
- RET (RET Produkte)
- Hintergrund
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Description: RET (ret proto-oncogene) is a member of the cadherin superfamily and a receptor tyrosine kinase, which are cell-surface molecules that transduce signals for cell growth and differentiation. It can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Ligands that bind the Ret receptor include the glial cell line-derived neurotropic factor (GDNF) and its congeners neurturin, persephin and artemin. Alterations in the corresponding Ret gene are associated with diseases including papillary thyroid carcinoma, multiple endocrine neoplasia (type 2A and 2B), familial medullary thyroid carcinoma and a congenital developmental disorder known as Hirschsprung
Aliases: RET
- Gen-ID
- 5979
- HGNC
- 5979
- UniProt
- P07949
- Pathways
- RTK Signalweg, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation
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