Survivin Antikörper

Produktnummer ABIN1724686

Produktdetails anti-Survivin Antikörper

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Survivin Antikörper ist unkonjugiert

Applikation: ELISA

Verwendungszweck: Survivin Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of Survivin expressed in E. Coli.

Klon: 2H5H2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Survivin Antikörper (ABIN1724686)

Karam, Lotan, Ashfaq, Sagalowsky, Shariat: "Survivin expression in patients with non-muscle-invasive urothelial cell carcinoma of the bladder." in: Urology, Vol. 70, Issue 3, pp. 482-6, (2007) (PubMed).

Piras, Murtas, Minerba, Ugalde, Floris, Maxia, Colombari, Perra, Sirigu: "Nuclear survivin is associated with disease recurrence and poor survival in patients with cutaneous malignant melanoma." in: Histopathology, Vol. 50, Issue 7, pp. 835-42, (2007) (PubMed).

Details zu Survivin

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Andere Bezeichnung: Survivin (BIRC5 Produkte)

Synonyme: AP14 antikoerper, API4 antikoerper, EPR-1 antikoerper, AAC-11 antikoerper, Api4 antikoerper, TIAP antikoerper, survivin40 antikoerper, bir5a antikoerper, survivin antikoerper, BIR1 antikoerper, Su2 antikoerper, XBIR1 antikoerper, XSurvivin1 antikoerper, Xsvv1 antikoerper, api4 antikoerper, bir1-A antikoerper, epr-1 antikoerper, svv1 antikoerper, xSurvivin antikoerper, xsurv antikoerper, Su1 antikoerper, birc5.2 antikoerper, svv2 antikoerper, xSurvivin2 antikoerper, bir5b antikoerper, SIX antikoerper, birc5.2-a antikoerper, birc5.2-b antikoerper, baculoviral IAP repeat containing 5 antikoerper, baculoviral IAP repeat-containing 5 antikoerper, baculoviral IAP repeat containing 5a antikoerper, baculoviral IAP repeat-containing 5, gene 1 L homeolog antikoerper, baculoviral IAP repeat containing 5 L homeolog antikoerper, baculoviral IAP repeat containing 5b antikoerper, baculoviral IAP repeat containing 5 S homeolog antikoerper, BIRC5 antikoerper, Birc5 antikoerper, birc5a antikoerper, birc5.1.L antikoerper, birc5.2.L antikoerper, birc5b antikoerper, birc5.2.S antikoerper

Hintergrund:

Description: Baculoviral IAP repeat-containing 5 (survivin). This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.

Aliases: API4, EPR-1, BIRC5

Gen-ID: 332

HGNC: 332

UniProt: O15392

Pathways: Apoptose, Zellzyklus, Nuclear Hormone Receptor Binding