EPH Receptor B2 Antikörper (AA 17-200)

Produktnummer ABIN1724695

Produktdetails anti-EPH Receptor B2 Antikörper

Target: EPH Receptor B2 (EPHB2)

Bindungsspezifität: AA 17-200

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EPH Receptor B2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC)

Verwendungszweck: EphB2 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of EphB2 (aa17-200) expressed in E. Coli.

Klon: 2D12C6

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-EPH Receptor B2 Antikörper (ABIN1724695)

Diehl, Bruno, Wilkinson, Loose, Wilting, Schweigerer, Klein: "Altered expression patterns of EphrinB2 and EphB2 in human umbilical vessels and congenital venous malformations." in: Pediatric research, Vol. 57, Issue 4, pp. 537-44, (2005) (PubMed).

Huusko, Ponciano-Jackson, Wolf, Kiefer, Azorsa, Tuzmen, Weaver, Robbins, Moses, Allinen, Hautaniemi, Chen, Elkahloun, Basik, Bova, Bubendorf, Lugli, Sauter, Schleutker, Ozcelik, Elowe, Pawson, Trent et al.: "Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer. ..." in: Nature genetics, Vol. 36, Issue 9, pp. 979-83, (2004) (PubMed).

Details zu EPH Receptor B2

Target: EPH Receptor B2 (EPHB2)

Andere Bezeichnung: EphB2 (EPHB2 Produkte)

Hintergrund:

Description: EphB2: EPH receptor B2. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.

Aliases: DRT, ERK, CAPB, Hek5

Gen-ID: 2048

HGNC: 2048

UniProt: P29323

Pathways: RTK Signalweg, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteine