Progesterone Receptor Antikörper (AA 731-909)
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- Target Alle Progesterone Receptor (PGR) Antikörper anzeigen
- Progesterone Receptor (PGR)
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Bindungsspezifität
- AA 731-909
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Progesterone Receptor Antikörper ist unkonjugiert
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Applikation
- ELISA
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of PGR (aa731-909) expressed in E. coli.
- Klon
- 2C11F11
- Isotyp
- IgG2b
- Top Product
- Discover our top product PGR Primärantikörper
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- Applikationshinweise
- ELISA: 1:10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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Progesterone receptor isoforms as a prognostic marker in human endometrial carcinoma." in: Cancer science, Vol. 97, Issue 12, pp. 1308-14, (2006) (PubMed).
: "Progesterone receptors (PR)-B and -A regulate transcription by different mechanisms: AF-3 exerts regulatory control over coactivator binding to PR-B." in: Molecular endocrinology (Baltimore, Md.), Vol. 20, Issue 11, pp. 2656-70, (2006) (PubMed).
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Progesterone receptor isoforms as a prognostic marker in human endometrial carcinoma." in: Cancer science, Vol. 97, Issue 12, pp. 1308-14, (2006) (PubMed).
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- Target
- Progesterone Receptor (PGR)
- Andere Bezeichnung
- PGR (PGR Produkte)
- Synonyme
- NR3C3 antikoerper, PR antikoerper, 9930019P03Rik antikoerper, BB114106 antikoerper, ENSMUSG00000074510 antikoerper, PR-A antikoerper, PR-B antikoerper, XPR-1 antikoerper, pgr antikoerper, xpr-2 antikoerper, LOC443444 antikoerper, PGR antikoerper, pg antikoerper, pr antikoerper, gb:dq017620 antikoerper, progesterone receptor antikoerper, progesterone receptor L homeolog antikoerper, PGR antikoerper, Pgr antikoerper, pgr.L antikoerper, pgr antikoerper
- Hintergrund
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Description: PGR: progesterone receptor. This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined.
Aliases: PR, NR3C3, PGR
- Gen-ID
- 5241
- HGNC
- 5241
- Pathways
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
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