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MAPK10 Antikörper (AA 28-233)

Name: MAPK10 Antikörper (AA 28-233)
Brand: antibodies-online
SKU: ABIN1724701
Price: 694.94 EUR
Availability: InStock

MAPK10 Reaktivität: Human WB, ELISA, ICC Wirt: Maus Monoclonal 10E4A4 unconjugated

Western blot analysis using MAPK10 mouse mAb against NIH/3T3 (1) and SKN-SH (2) cell lysate. (MAPK10 Antikörper (AA 28-233))

Immunofluorescence staining of methanol-fixed A431 (left) and Hela (right) cells showing cytoplasmic and membrane localization. (MAPK10 Antikörper (AA 28-233))

2 Abbildungen

(2 Referenzen)

Produktnummer ABIN1724701

Datenblatt (PDF)

Target Alle MAPK10 Antikörper anzeigen

MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
Bindungsspezifität
15

11

8

5

4

2

1

1

1

1

1

1

1

1

1

1

1
AA 28-233
Reaktivität
63

50

34

2

2

2

2

2

2

2

1

1

1

1

1
Human
Wirt
67

7

3
Maus
Passende Sekundärantikörper
Klonalität
61

18
Monoklonal
Konjugat
34

9

5

4

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
Dieser MAPK10 Antikörper ist unkonjugiert
Applikation
47

38

26

13

13

9

8

6

4

4

2

2

1

1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Verwendungszweck

MAPK10 Antibody

Aufreinigung

Ascitic fluid

Immunogen

Purified recombinant fragment of human MAPK10 (aa28-233) expressed in E. Coli.

Klon

10E4A4

Isotyp

IgG1

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Applikationshinweise

ELISA: 1/10000
ICC: 1/200 - 1/1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Tamma, Kalyanaraman, Pahwa, Dominguez, Modesto: "The lectin jacalin induces phosphorylation of ERK and JNK in CD4+ T cells." in: Journal of leukocyte biology, Vol. 73, Issue 5, pp. 682-8, (2003) (PubMed).

Kinet, Bernard, Mongellaz, Perreau, Goldman, Taylor: "gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4(+) lymphocytes." in: Blood, Vol. 100, Issue 7, pp. 2546-53, (2002) (PubMed).
Target

MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Andere Bezeichnung

MAPK10 (MAPK10 Produkte)

Hintergrund

Description: MAPK10: mitogen-activated protein kinase 10, also known as JNK3, JNK3A, PRKM10, p54bSAPK. Entrez Protein NP_002744. It is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Aliases: JNK3, JNK3A, PRKM10, p54bSAPK

Molekulargewicht

53kDa

Gen-ID

5602

NCBI Accession

NP_002744

HGNC

5602

UniProt

P53779

Pathways

MAPK Signalweg, WNT Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades