MAPK10 Antikörper (AA 28-233)

Produktnummer ABIN1724701

Produktdetails anti-MAPK10 Antikörper

Target: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Bindungsspezifität: AA 28-233

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MAPK10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Verwendungszweck: MAPK10 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human MAPK10 (aa28-233) expressed in E. Coli.

Klon: 10E4A4

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-MAPK10 Antikörper (ABIN1724701)

Tamma, Kalyanaraman, Pahwa, Dominguez, Modesto: "The lectin jacalin induces phosphorylation of ERK and JNK in CD4+ T cells." in: Journal of leukocyte biology, Vol. 73, Issue 5, pp. 682-8, (2003) (PubMed).

Kinet, Bernard, Mongellaz, Perreau, Goldman, Taylor: "gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4(+) lymphocytes." in: Blood, Vol. 100, Issue 7, pp. 2546-53, (2002) (PubMed).

Details zu MAPK10

Target: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Andere Bezeichnung: MAPK10 (MAPK10 Produkte)

Synonyme: MAPK10 antikoerper, zgc:123234 antikoerper, DKFZp459H0638 antikoerper, Jnk3 antikoerper, SAPKC antikoerper, SAPb antikoerper, Serk2 antikoerper, JNK3 antikoerper, JNK3A antikoerper, PRKM10 antikoerper, SAPK1b antikoerper, p493F12 antikoerper, p54bSAPK antikoerper, C230008H04Rik antikoerper, JNK3B1 antikoerper, JNK3B2 antikoerper, SAPK(beta) antikoerper, ATMPK10 antikoerper, MAP kinase 10 antikoerper, mitogen-activated protein kinase 8 S homeolog antikoerper, mitogen-activated protein kinase 10 antikoerper, mitogen activated protein kinase 10 antikoerper, MAP kinase 10 antikoerper, mapk8.S antikoerper, MAPK10 antikoerper, mapk10 antikoerper, Mapk10 antikoerper, MPK10 antikoerper

Hintergrund:

Description: MAPK10: mitogen-activated protein kinase 10, also known as JNK3, JNK3A, PRKM10, p54bSAPK. Entrez Protein NP_002744. It is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Aliases: JNK3, JNK3A, PRKM10, p54bSAPK

Molekulargewicht: 53kDa

Gen-ID: 5602

NCBI Accession: NP_002744

HGNC: 5602

UniProt: P53779

Pathways: MAPK Signalweg, WNT Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades