Src Antikörper (AA 10-193)
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- Target Alle Src Antikörper anzeigen
- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
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Bindungsspezifität
- AA 10-193
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Src Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of SRC (aa10-193) expressed in E. coli.
- Klon
- 5D10C4
- Isotyp
- IgG2a
- Top Product
- Discover our top product Src Primärantikörper
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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SRC tyrosine kinase inhibitor, m475271, suppresses subcutaneous growth and production of lung metastasis via inhibition of proliferation, invasion, and vascularization of human lung adenocarcinoma ..." in: Clinical & experimental metastasis, Vol. 22, Issue 3, pp. 195-204, (2005) (PubMed).
: "c-Src regulates constitutive and EGF-mediated VEGF expression in pancreatic tumor cells through activation of phosphatidyl inositol-3 kinase and p38 MAPK." in: Pancreas, Vol. 31, Issue 3, pp. 263-74, (2005) (PubMed).
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SRC tyrosine kinase inhibitor, m475271, suppresses subcutaneous growth and production of lung metastasis via inhibition of proliferation, invasion, and vascularization of human lung adenocarcinoma ..." in: Clinical & experimental metastasis, Vol. 22, Issue 3, pp. 195-204, (2005) (PubMed).
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- Target
- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
- Andere Bezeichnung
- SRC (Src Produkte)
- Synonyme
- AW259666 antikoerper, pp60c-src antikoerper, C-src1 antikoerper, CG7524 antikoerper, D-Src64B antikoerper, D-src antikoerper, DSRC64 antikoerper, DSrc antikoerper, DSrc64 antikoerper, DSrc64B antikoerper, Dm SRC1 antikoerper, DmHD-358 antikoerper, Dmel\CG7524 antikoerper, Dsrc antikoerper, Dsrc64 antikoerper, Dsrc64B antikoerper, HD-358 antikoerper, MRE5 antikoerper, SRC 64B antikoerper, Src antikoerper, Src1 antikoerper, Src64 antikoerper, c-src antikoerper, dSrc antikoerper, dsrc antikoerper, src antikoerper, src1 antikoerper, src64 antikoerper, src64B antikoerper, src64b antikoerper, ASV antikoerper, SRC1 antikoerper, c-SRC antikoerper, p60-Src antikoerper, c-Src antikoerper, PP60C-SCR antikoerper, SDR antikoerper, SRC proto-oncogene, non-receptor tyrosine kinase antikoerper, uncharacterized LOC5574802 antikoerper, proto-oncogene tyrosine-protein kinase src antikoerper, Rous sarcoma oncogene antikoerper, Src oncogene at 64B antikoerper, SRC antikoerper, LOC5574802 antikoerper, CpipJ_CPIJ010659 antikoerper, Src antikoerper, Src64B antikoerper
- Substanzklasse
- Viral Protein
- Hintergrund
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Description: SRC: v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian). This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Aliases: ASV, SRC1, c-SRC, p60-Src
- Gen-ID
- 6714
- HGNC
- 6714
- Pathways
- JAK-STAT Signalweg, Neurotrophin Signalübertragung, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagie, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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